MURAL - Maynooth University Research Archive Library



    Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents


    Elmes, Robert B.P. and Orange, Kim N. and Cloonan, Suzanne M. and Williams, D. Clive and Gunnlaugsson, Thorfinnur (2011) Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents. Journal of the American Chemical Society, 133 (40). pp. 15862-15865. ISSN 0002-7863

    [img]
    Preview
    Download (4MB) | Preview


    Share your research

    Twitter Facebook LinkedIn GooglePlus Email more...



    Add this article to your Mendeley library


    Abstract

    The synthesis and photophysical and biological investigation of Ru(II)-polypyridyl stabilized watersoluble, luminescent gold nanoparticles (AuNPs) are described. These structures bind to DNA and undergo rapid cellular uptake, being localized within the cell cytoplasm and nucleus within 4 h.

    Item Type: Article
    Additional Information: The definitive version of this article is available at Elmes, R. B. P., Orange, K. N., Cloonan, S. M., Williams, D. C., Gunnlaugsson, T. (2011) 'Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents'. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133:15862 - 15865. We thank the Science Foundation Ireland (SFI RFP 2009), HEA PRTLI Cycle 4, The Irish Research Council for Science, Engineering and Technology (IRCSET Postgraduate Studentship to R.B.P.E.), and TCD for financial support.
    Keywords: Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; DNA Binding Abilities; Application; Cellular Imaging Agents; AuNPs;
    Academic Unit: Faculty of Science and Engineering > Chemistry
    Item ID: 5618
    Identification Number: https://doi.org/10.1021/ja2061159
    Depositing User: Robert Elmes
    Date Deposited: 15 Dec 2014 16:45
    Journal or Publication Title: Journal of the American Chemical Society
    Publisher: American Chemical Society
    Refereed: Yes
    Funders: Science Foundation Ireland, Irish Research Council for Science, Engineering and Technology, Higher Education Authority
    URI:

    Repository Staff Only(login required)

    View Item Item control page

    Downloads

    Downloads per month over past year