MURAL - Maynooth University Research Archive Library



    Metal-Free “Click” Chemistry: Efficient Polymer Modification via 1,3-Dipolar Cycloaddition of Nitrile Oxides and Alkynes


    Singh, Ishwar and Zarafshani, Zoya and Lutz, Jean-François and Heaney, Frances (2009) Metal-Free “Click” Chemistry: Efficient Polymer Modification via 1,3-Dipolar Cycloaddition of Nitrile Oxides and Alkynes. Macromolecules, 42 (15). pp. 5411-5413. ISSN 0024-9297

    [img]
    Preview
    Download (829kB) | Preview


    Share your research

    Twitter Facebook LinkedIn GooglePlus Email more...



    Add this article to your Mendeley library


    Abstract

    Polymer chemistry, probably more than any other chemical discipline, relies on highly efficient organic reactions.1 Indeed, typical macromolecular reactions such as polymer growth (i.e., chain- or step-growth), polymer modification (i.e side-chains or chain-ends) and chain-chain coupling (i.e., block copolymer synthesis, bioconjugation) generally require high-yield and highly specific chemical reactions.2 In that context, it comes as no surprise thatmodular reactions of the “click”-type3 have recently been gaining popularity in polymer science. For instance, more than 300 articles, describing the relevance of copper-catalyzed azide/alkyne cycloadditions (CuAAC) in polymer synthesis, have been published within the last five years.4 These archetypal “click” reactions open multiple possibilities in terms of macromolecular engineering.

    Item Type: Article
    Keywords: Metal-Free; “Click” Chemistry; Polymer Modification; 1,3-Dipolar Cycloaddition; Nitrile Oxides; ;Alkynes;
    Academic Unit: Faculty of Science and Engineering > Chemistry
    Item ID: 7966
    Identification Number: https://doi.org/10.1021/ma9013912
    Depositing User: Dr. Frances Heaney
    Date Deposited: 24 Feb 2017 16:32
    Journal or Publication Title: Macromolecules
    Publisher: American Chemical Society
    Refereed: Yes
    Funders: German Research Foundation, Science Foundation Ireland (SFI)
    URI:

    Repository Staff Only(login required)

    View Item Item control page

    Downloads

    Downloads per month over past year