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    Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine


    Heaney, Frances and Bourke, Sharon and Burke, Cathriona and Cunningham, Desmond and McArdle, Patrick (1998) Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine. Journal of the Chemical Society, Perkin Transactions 1, 1. pp. 2255-2258. ISSN 0300-922X

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    Abstract

    Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular ‘conjugate’ addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.

    Item Type: Article
    Keywords: imidazo[1,2-c] pyrimidinones; chloropyrimidine; electron poor ω-allylic amine;
    Academic Unit: Faculty of Science and Engineering > Chemistry
    Item ID: 7969
    Identification Number: https://doi.org/10.1039/A802750A
    Depositing User: Dr. Frances Heaney
    Date Deposited: 24 Feb 2017 16:30
    Journal or Publication Title: Journal of the Chemical Society, Perkin Transactions 1
    Publisher: Royal Society of Chemistry
    Refereed: Yes
    Funders: Forbairt, Eolas
    URI:

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