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    Synthesis of novel chiral quaternary phosphonium fluorides: reagents for simple asymmetric nucleophilic fluorination reactions


    Beaumont, Andrew J. and Kiely, Christopher and Rooney, A. Denise (2001) Synthesis of novel chiral quaternary phosphonium fluorides: reagents for simple asymmetric nucleophilic fluorination reactions. Journal of Fluorine Chemistry, 108 (1). pp. 47-50. ISSN 0022-1139

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    Abstract

    The novel chiral quaternary salt (RP)-benzylmenthylmethylphenylphosphonium fluoride was synthesised. The compound was used in the asymmetric nucleophilic fluorination of 2-bromopropiophenone to give 2-fluoropropiophenone in a 35% yield with [α]D20=+1.94°.

    Item Type: Article
    Keywords: Asymmetric; Nucleophilic; Fluorination; Chiral; Phosphonium; Fluoride;
    Academic Unit: Faculty of Science and Engineering > Chemistry
    Item ID: 7984
    Identification Number: https://doi.org/10.1016/S0022-1139(00)00401-2
    Depositing User: Dr. Denise Rooney
    Date Deposited: 01 Mar 2017 16:03
    Journal or Publication Title: Journal of Fluorine Chemistry
    Publisher: Elsevier
    Refereed: Yes
    URI:

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