Kavanagh, Kevin and Reeves, Emer P. (2007) Insect and Mammalian Innate Immune Responses Are Much Alike. Microbe, 2 (12). pp. 596-599. ISSN 1558-7460

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Abstract

The innate immune systems of mammals and insects have several features in common. Both insect hemocytes and mammalian neutrophils engulf and kill pathogens, and both types of cell produce superoxide, using extraordinarily similar p47 and p67 proteins. Larvae of the greater wax moth Galleria mellonella provide a model system for evaluating familiar bacterial and fungal pathogens as well as for testing candidate antimicrobials. Insect immune systems function cooperatively and exhibit both humoral and cellular components.

Item Type:	Article
Keywords:	Insect; Mammal; Innate Immune Responses;
Academic Unit:	Faculty of Science and Engineering > Biology
Item ID:	11133
Depositing User:	Dr. Kevin Kavanagh
Date Deposited:	04 Oct 2019 16:23
Journal or Publication Title:	Microbe
Publisher:	American Society for Microbiology
Refereed:	Yes
Funders:	Higher Education Authority (HEA)
URI:
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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