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    Investigation of events in the EEG signal correlated with changes in both oxygen and glucose in the brain


    Valente, Sabrina and Ringwood, John and Mangourova, Violeta and Lowry, John P. (2012) Investigation of events in the EEG signal correlated with changes in both oxygen and glucose in the brain. In: ISSC 2012, 28-29 June, 2012, NUI Maynooth.

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    Abstract

    Since the brain has no constant energy reserves, a continuous supply of energy substrates is central to all processes that maintain the functionality of the neuronal cells. EEG has been found to be tightly related to variations in the concentration of the energy substrates such as oxygen and glucose. Prediction of neural activation is particularly useful as it could contribute significantly in the prevention, stabilization, or treatment of diseases such as Alzheimer's disease, migraine headache, and ischemic stroke, in which signaling between neurons and brain vessels is threatened because of dysfunctions that affect the neuronal, astroglial, and/or vascular components of the neurovascular unit. This work deals with investigation of events in the EEG signal correlated with changes in both oxygen and glucose signals in the brain. The topic is to implement a model that through measures of oxygen and glucose in the brain of rats allow to achieve a good estimation of the neural signals, which reflecting the simultaneous metabolic changes, during spontaneous oscillation and electrical stimulation.

    Item Type: Conference or Workshop Item (Paper)
    Keywords: neuronal activation; brain metabolism; energy substrates; system identification;
    Academic Unit: Faculty of Science and Engineering > Electronic Engineering
    Item ID: 3864
    Depositing User: Professor John Ringwood
    Date Deposited: 17 Sep 2012 11:04
    Refereed: Yes
    URI:

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