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    Solid phase strain promoted “click” modification of DNA via [3+2]-nitrile oxide–cyclooctyne cycloadditions


    Singh, Ishwar and Heaney, Frances (2011) Solid phase strain promoted “click” modification of DNA via [3+2]-nitrile oxide–cyclooctyne cycloadditions. Chemical Communications, 47. pp. 2706-2708. ISSN 1359-7345

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    Abstract

    Biocompatible, strain promoted cyclooctyne–nitrile oxide click chemistry is demonstrated as a rapid and reliable method for DNA conjugation on the solid phase.

    Item Type: Article
    Keywords: Solid phase strain; “click” modification of DNA; [3+2]-nitrile oxide–cyclooctyne cycloadditions;
    Academic Unit: Faculty of Science and Engineering > Chemistry
    Item ID: 4288
    Depositing User: Dr. Frances Heaney
    Date Deposited: 08 Apr 2013 15:39
    Journal or Publication Title: Chemical Communications
    Publisher: Royal Society of Chemstry
    Refereed: Yes
    URI:

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