Dolan, Niamh and McGinley, John and Stephens, John C. and Kavanagh, Kevin and Hurley, Daniel and Maher, Niall
(2014)
Synthesis, characterisation and antimicrobial studies of organotin(IV)
complexes with 1,10-phenanthroline derivatives.
Inorganica Chimica Acta, 409 (Part B).
pp. 276-284.
ISSN 0020-1693
Abstract
The synthesis of several diorganotin(IV) dicarboxylate compounds, including acetates and nicotinates as
well as diorganotin(IV) dichloride complexes of the ligands phen, dione and dppz were undertaken. Several
difficulties in either the syntheses or complexation reactions with the organic ligands were encountered.
The diorganotin(IV) dichloride complexes of the ligands (R2SnCl2L where R = Me, n-Bu or Ph and
L = phen, dione or dppz) were tested against Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa.
The dibutyltin(IV) derivatives exhibited the broadest range of activity in comparison to the
dimethyltin(IV) or diphenyltin(IV) derivatives. The addition of the nicotinate group did not promote
activity against any of the bacteria. Furthermore, only in the case of Ph2SnCl2 dione was there improved
activity compared to the organic ligand itself.
| Item Type: |
Article
|
| Additional Information: |
The definitive published version of this article is available at DOI: 10.1016/j.ica.2013.09.038 |
| Keywords: |
Organotin halides and acetates; 1,10-Phenanthroline derivatives; NMR studies; Biological testing; |
| Academic Unit: |
Faculty of Science and Engineering > Biology |
| Item ID: |
6893 |
| Identification Number: |
https://doi.org/10.1016/j.ica.2013.09.038 |
| Depositing User: |
Dr. Kevin Kavanagh
|
| Date Deposited: |
20 Jan 2016 13:20 |
| Journal or Publication Title: |
Inorganica Chimica Acta |
| Publisher: |
Elsevier |
| Refereed: |
Yes |
| URI: |
|
| Use Licence: |
This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available
here |
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