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    Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2-year surveillance study


    Ellabib, M.S. and Agaj, M. and Khalifa, Z. and Kavanagh, K. (2002) Yeasts of the genus Candida are the dominant cause of onychomycosis in Libyan women but not men: results of a 2-year surveillance study. British Journal of Dermatology, 146 (6). pp. 1038-1041. ISSN 0007-0963

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    Abstract

    BACKGROUND: The reported frequency of recovery of fungi from infected nails varies according to the geographical area. OBJECTIVES: To establish the nature of the causal agents in a sample of the Libyan population presenting with suspected onychomycosis. METHODS: Samples were taken from the infected fingernails of 648 patients attending the Tripoli Medical Centre. RESULTS: Samples from 500 patients proved positive for fungi following culturing, while 476 were potassium hydroxide and culture positive. Of the culture-positive samples, yeasts of the genus Candida (C. albicans, C. parapsilosis, C. glabrata, C. guillermondii and C. tropicalis) were the dominant cause of this condition in women (417 of 434, 96%) but were responsible for only a minority of cases in men (three of 66, 5%). In contrast, dermatophytes (Trichophyton violaceum, T. rubrum, T. mentagrophytes and Microsporum canis) were responsible for this condition in the majority of cases in men (53 of 66, 80%) but only 3% (15 of 434) of cases in women. The mould Aspergillus nidulans was isolated from the nails of 10 (15%) men and two (0.5%) women. CONCLUSIONS: The data obtained in this study reveal an almost total separation of the aetiological agents responsible for onychomycosis based on gender.

    Item Type: Article
    Keywords: Candida; dermatophytes; Libya; onychomycosis; Trichophyton;
    Academic Unit: Faculty of Science and Engineering > Biology
    Item ID: 7596
    Identification Number: https://doi.org/10.1046/j.1365-2133.2002.04688.x
    Depositing User: Dr. Kevin Kavanagh
    Date Deposited: 02 Nov 2016 16:41
    Journal or Publication Title: British Journal of Dermatology
    Publisher: Wiley
    Refereed: Yes
    URI:

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