Coogan, Andrew and Baird, Alison and Popa-Wagner, Aurel and Thome, Johannes (2016) Circadian rhythms and attention deficit hyperactivity disorder: The what, the when and the why. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 67 (3). pp. 74-81. ISSN 0278-5846

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Abstract

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental condition characterised by impulsivity, inattention and hyperactivity. Aside from these core psychopathologies, sleep disturbances are found to be highly comorbid with ADHD, and indeed dysregulated sleep may contribute to some of the symptoms of the disorder. It is not clear how sleep disturbances come to be so common in ADHD, but one putative mechanism is through the circadian timekeeping system. This system underpins the generation of near 24-hour rhythms in a host of physiological, behavioural and psychological parameters, and is a key determinant of the sleep/wake cycle. In this paper we review the evidence for sleep and circadian rhythm disturbance in ADHD, examine the possible mechanistic links between these factors and the disorder and discuss future directions through which the circadian clock can be targetted for ADHD symptom relief.

Item Type:	Article
Keywords:	ADHD; Circadian; Sleep;
Academic Unit:	Faculty of Science and Engineering > Psychology
Item ID:	10733
Identification Number:	https://doi.org/10.1016/j.pnpbp.2016.01.006
Depositing User:	Dr. Andrew Coogan
Date Deposited:	16 Apr 2019 15:54
Journal or Publication Title:	Progress in Neuro-Psychopharmacology and Biological Psychiatry
Publisher:	Elsevier
Refereed:	Yes
URI:	https://www.sciencedirect.com/
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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