Kumawat, Lokesh K. and Wynne, Conor and Cappello, Emanuele and Fisher, Peter and Brennan, Luke E. and Strofaldi, Alessandro and McManus, Jennifer J. and Hawes, Chris S. and Jolliffe, Katrina A. and Gunnlaugsson, Thorfinnur and Elmes, Robert B. P. (2021) Squaramide‐Based Self‐Associating Amphiphiles for Anion Recognition. ChemPlusChem, 86 (8). pp. 1058-1068. ISSN 2192-6506

Preview

Download (2MB) | Preview

Abstract

The synthesis and characterisation of two novel self-assembled amphiphiles (SSAs) SQS-1 and SQS-2 are reported. Both compounds, based on the squaramide motif, were fully soluble in a range of solvents and were shown to undergo self-assembly through a range of physical techniques. Self-assembly was shown to favour the formation of crystalline domains on the nanoscale but also fibrillar film formation, as suggested by SEM analysis. Moreover, both SQS-1 and SQS-2 were capable of anion recognition in DMSO solution as demonstrated using 1 HNMR and UV/Vis absorption spectroscopy, but displayed lower binding affinities for various anions when compared against other squaramide based receptors. In more competitive solvent mixtures SQS-1 gave rise to a colourimetric response in the presence of HPO4 2 anion when compared against other biologically relevant anions

Item Type:	Article
Additional Information:	Cite as: L. K. Kumawat, C. Wynne, E. Cappello, P. Fisher, L. E. Brennan, A. Strofaldi, J. J. McManus, C. S. Hawes, K. A. Jolliffe, T. Gunnlaugsson, R. B. P. Elmes, ChemPlusChem 2021, 86, 1058.
Keywords:	Chemistry; self-assembled amphiphiles; squaramide motif; Anion Recognition;
Academic Unit:	Faculty of Science and Engineering > Chemistry Faculty of Science and Engineering > Research Institutes > Human Health Institute
Item ID:	17384
Identification Number:	https://doi.org/10.1002/cplu.202100275
Depositing User:	Robert Elmes
Date Deposited:	06 Jul 2023 13:39
Journal or Publication Title:	ChemPlusChem
Publisher:	Wiley
Refereed:	Yes
URI:	Publisher
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

Repository Staff Only(login required)

Item control page

Downloads

Origin of downloads