McCormack, Adam T. and Stephens, John C. (2024) The continuous flow synthesis of azos. Journal of Flow Chemistry. ISSN 2062-249X

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Abstract

Azo compounds find use in many areas of science, displaying crucial properties for important applications as photoconductive organic pigments, fluorescent quenchers, paints, cosmetics, inks, and in the large and valuable dye industry. Due to the unstable intermediates, and the exothermic and fast reactions used in their synthesis, high value azo compounds are excellent candidates for continuous flow manufacturing. This comprehensive review covers the progress made to date on developing continuous flow systems for azo synthesis and reflects on the main challenges still to be addressed, including scale up, conversion, product purity, and environmental impact. The further development of integrated continuous flow processes has the potential to help tackle these challenges and deliver improved methods for azo compound generation.

Item Type:	Article
Keywords:	Continuous flow synthesis; Azo; Dye; Diazonium; Microreactor;
Academic Unit:	Faculty of Science and Engineering > Chemistry
Item ID:	18101
Identification Number:	https://doi.org/10.1007/s41981-024-00307-2
Depositing User:	Dr John Stephens
Date Deposited:	30 Jan 2024 15:28
Journal or Publication Title:	Journal of Flow Chemistry
Publisher:	Akadémiai Kiadó [Co-Publisher] Springer [Primary Co-Publisher]
Refereed:	Yes
URI:	Publisher
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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