Nakaya, T. and Fotheringham, Stewart and Brunsdon, Chris and Charlton, Martin
(2005)
Geographically weighted Poisson regression for disease
association mapping.
Statistics in Medicine, 24 (17).
pp. 2695-2717.
ISSN 0277-6715
Abstract
This paper describes geographically weighted Poisson regression (GWPR) and its semi-parametric variant
as a new statistical tool for analysing disease maps arising from spatially non-stationary processes.
The method is a type of conditional kernel regression which uses a spatial weighting function to estimate
spatial variations in Poisson regression parameters. It enables us to draw surfaces of local parameter
estimates which depict spatial variations in the relationships between disease rates and socio-economic
characteristics. The method therefore can be used to test the general assumption made, often without
question, in the global modelling of spatial data that the processes being modelled are stationary over
space. Equally, it can be used to identify parts of the study region in which ‘interesting’ relationships
might be occurring and where further investigation might be warranted. Such exceptions can easily be
missed in traditional global modelling and therefore GWPR provides disease analysts with an important
new set of statistical tools. We demonstrate the GWPR approach applied to a dataset of working-age
deaths in the Tokyo metropolitan area, Japan. The results indicate that there are signifcant spatial
variations (that is, variation beyond that expected from random sampling) in the relationships between
working-age mortality and occupational segregation and between working-age mortality and unemployment
throughout the Tokyo metropolitan area and that, consequently, the application of traditional
‘global’ models would yield misleading results.
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