Cochrane, Andy, Robertson, Ian H. and Coogan, Andrew (2012) Association between circadian rhythms, sleep and cognitive impairment in healthy older adults: an actigraphic study. Journal of Neural Transmission, 119. pp. 1233-1239. ISSN 0300-9564
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Abstract
There is increasing evidence for the relationship
between circadian rhythm disturbance and cognitive decline
in the older adult. This study measured circadian activity
rhythms in a small group of healthy community-dwelling
older adults (n = 26). Each participant completed a battery
of neuropsychological tests and completed sleep diaries and
6 days of actigraphy. Ten participants were identified as
having very early signs of cognitive decline as indicated by
their performance on the memory tests. Results showed
minimal differences on the sleep/activity and circadian
parameters across the two groups (declined vs. intact),
although there was a significant difference in the acrophase
between the declined and intact groups. These findings,
although exploratory, suggest that very subtle changes in
circadian rhythm may be detected in older adults showing
pre-clinical changes in cognitive performance.
Item Type: | Article |
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Additional Information: | The definitive version of this article is available at DOI: 10.1007/s00702-012-0802-2 |
Keywords: | Sleep–wake; Circadian; Actigraphy; Older adults; Cognition; |
Academic Unit: | Faculty of Science and Engineering > Psychology |
Item ID: | 5977 |
Identification Number: | 10.1007/s00702-012-0802-2 |
Depositing User: | Andy Cochrane |
Date Deposited: | 23 Mar 2015 15:55 |
Journal or Publication Title: | Journal of Neural Transmission |
Publisher: | Springer Verlag |
Refereed: | Yes |
Related URLs: | |
URI: | https://mural.maynoothuniversity.ie/id/eprint/5977 |
Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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