MURAL - Maynooth University Research Archive Library



    Selective Michael additions to alkylidenemalonates using thiourea-based bifunctional organocatalysts


    Gavin, Declan P. and Stephens, John C. (2013) Selective Michael additions to alkylidenemalonates using thiourea-based bifunctional organocatalysts. Arkivoc, 4. pp. 76-87. ISSN 1551-7012

    [img]
    Preview
    		 Download (423kB) | Preview


    Share your research

    Twitter Facebook LinkedIn GooglePlus Email more...



    Add this article to your Mendeley library


    Abstract

    Bifunctional thiourea catalysts have been found to be excellent promoters of the challenging Michael addition to alkylidenemalonates giving high yields of up to 99%. Substrate structure was important for enantiodiscrimination, with aryl alkylidenemalonate acceptors furnishing products with ee values of up to 73%.

    Item Type: Article
    Additional Information: Published under a Creative Commons Attribution Non-Commercial License
    Keywords: Organocatalysis; alkylidenemalonates; β-diketones; nitromethane; Michael addition; bifunctional thiourea catalysts;
    Academic Unit: Faculty of Science and Engineering > Chemistry
    Item ID: 6335
    Depositing User: Dr John Stephens
    Date Deposited: 07 Sep 2015 09:13
    Journal or Publication Title: Arkivoc
    Publisher: Arkat USA Inc.
    Refereed: Yes
    URI:
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

    Repository Staff Only(login required)

    View Item Item control page

    Downloads

    Downloads per month over past year

    Origin of downloads

    Altmetric
    MURAL - Maynooth University Research Archive Library is powered by EPrints 3 which is developed by the School of Electronics and Computer Science at the University of Southampton. More information and software credits.