Murphy, Jennifer and Blanchard, Mathieu M. and Rawdon, Caroline and Kavanagh, Fergal and Kelleher, Ian and Clarke, Mary C. and Roche, Richard and Cannon, Mary
(2012)
Language processing abnormalities in adolescents with psychotic-like experiences:
An event related potential study.
Schizophrenia Research, 137.
pp. 91-96.
ISSN 0920-9964
Abstract
Language impairments are a well established finding in patients with schizophrenia and in individuals at-risk
for psychosis. A growing body of research has revealed shared risk factors between individuals with
psychotic-like experiences (PLEs) from the general population and patients with schizophrenia. In particular,
adolescents with PLEs have been shown to be at an increased risk for later psychosis. However, to date there
has been little information published on electrophysiological correlates of language comprehension in this
at-risk group. A 64 channel EEG recorded electrical activity while 37 (16 At-Risk; 21 Controls) participants
completed the British Picture Vocabulary Scale (BPVS-II) receptive vocabulary task. The P300 component
was examined as a function of language comprehension. The at-risk group were impaired behaviourally on
receptive language and were characterised by a reduction in P300 amplitude relative to the control group.
The results of this study reveal electrophysiological evidence for receptive language deficits in adolescents
with PLEs, suggesting that the earliest neurobiological changes underlying psychosis may be apparent in
the adolescent period.
| Item Type: |
Article
|
| Additional Information: |
The definitive version of this article is available at DOI: 10.1016/j.schres.2012.01.017 |
| Keywords: |
Psychosis; P300; Psychotic-like experiences; Schizophrenia; Language; PLEs; |
| Academic Unit: |
Faculty of Science and Engineering > Psychology |
| Item ID: |
6796 |
| Identification Number: |
https://doi.org/10.1016/j.schres.2012.01.017 |
| Depositing User: |
Richard Roche
|
| Date Deposited: |
14 Jan 2016 10:51 |
| Journal or Publication Title: |
Schizophrenia Research |
| Publisher: |
Elsevier |
| Refereed: |
Yes |
| URI: |
|
| Use Licence: |
This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available
here |
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