McLoone, Violeta I. and Ringwood, John (2012) A system identification approach to baroreflex sensitivity estimation. Proceedings of the Irish Signals and Systems Conference.

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Abstract

The body contains a bewildering array of regulatory systems which maintain homeostasis. There is considerable difficulty in isolating a single control loop for analysis, due to the interactions with other systems/loops. One important such regulatory loop is the baroreflex, and baroreflex sensitivity is a characteristic open-loop parameter which can help us to assess the health of the baroreflex. A diverse range of methods have been proposed to determine baroreflex sensitivity from experimental data. Unfortunately, there appears to be little consistency of result among the different methods and some explanation can be found in the nature of the problem: In most cases, an attempt is being made to determine open-loop measures from a system operating in closed-loop, subject to poor excitation. In this paper we propose a strict procedure, based on a rigourous mathematical framework, from which reliable estimates of baroreflex sensitivity can be obtained. A comparison with other methods for baroreflex sensitivity estimation, using the EuroBaVar data set, is performed.

Item Type:	Article
Keywords:	Baroreflex sensitivity; system identification;
Academic Unit:	Faculty of Science and Engineering > Electronic Engineering
Item ID:	6866
Depositing User:	Professor John Ringwood
Date Deposited:	19 Jan 2016 16:47
Journal or Publication Title:	Proceedings of the Irish Signals and Systems Conference
Publisher:	ISSC
Refereed:	Yes
URI:	Publisher
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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