McManus, Jennifer and Rädler, Joachim O. and Dawson, Kenneth A. (2004) Observation of a Rectangular Columnar Phase in a DNA−Calcium−Zwitterionic Lipid Complex. Journal of the American Chemical Society, 126 (49). pp. 15966-15967. ISSN 0002-7863

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Abstract

In the presence of calcium, DNA and unilamellar liposomes of the zwitterionic lipid DPPC form a complex in which DNA strands are embedded between a lamellar phase of DPPC. In some complexes, in-plane alignment of the DNA strands occurs, where a DNA-DNA interaxial distance can be measured using small-angle X-ray scattering. Here we report a higher level of DNA organization, with a rectangular columnar phase of DNA identified within this complex structure. This observation is important in view of recent interests in creating new synthetic systems at the interface of biology.

Item Type:	Article
Keywords:	Rectangular Columnar Phase; DNA−Calcium−Zwitterionic Lipid Complex; DNA; Calcium;
Academic Unit:	Faculty of Science and Engineering > Chemistry
Item ID:	7897
Identification Number:	https://doi.org/10.1021/ja046105+
Depositing User:	Jennifer McManus
Date Deposited:	10 Feb 2017 15:45
Journal or Publication Title:	Journal of the American Chemical Society
Publisher:	American Chemical Society
Refereed:	Yes
URI:	http://pubs.acs.org
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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