Heaney, Frances and Bourke, Sharon and Burke, Cathriona and Cunningham, Desmond and McArdle, Patrick (1998) Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine. Journal of the Chemical Society, Perkin Transactions 1, 1. pp. 2255-2258. ISSN 0300-922X

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Abstract

Synthesis of the title ring system by a sequential intermolecular nucleophilic displacement and intramolecular ‘conjugate’ addition has been achieved both as a one pot and as a stepwise procedure; an X-ray structure determination has been carried out to distinguish between the possible isomeric structures 8c-I and 8c-II.

Item Type:	Article
Keywords:	imidazo[1,2-c] pyrimidinones; chloropyrimidine; electron poor ω-allylic amine;
Academic Unit:	Faculty of Science and Engineering > Chemistry
Item ID:	7969
Identification Number:	https://doi.org/10.1039/A802750A
Depositing User:	Dr. Frances Heaney
Date Deposited:	24 Feb 2017 16:30
Journal or Publication Title:	Journal of the Chemical Society, Perkin Transactions 1
Publisher:	Royal Society of Chemistry
Refereed:	Yes
Funders:	Forbairt, Eolas
URI:	http://pubs.rsc.org
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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