McLoone, Eibhlin and O'Keefe, M. and Donoghue, V. and McLoone, Sean F. and Horgan, N. and Lanigan, B. (2006) RetCam image analysis of optic disc morphology in premature infants and its relation to ischaemic brain injury. British Journal of Ophthalmology, 90. pp. 465-471.

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Abstract

To assess optic disc characteristics in premature infants with and without ischaemic brain injury and to evaluate the role of optic disc morphology in dating the injury. RetCam fundal images, cranial untrasounds and magnetic resonance imaging (MR) of 109 premature infants were analysed. The study cohort was divided into subgroups depending on the presence or absence of periventricular leucomalacia (PVL) and intraventricular haemorrhage (IVH). The control group consisted of infants with normal neuroimaging at term and 2 years of age. Using the image analysis software of the RetCam, optic disc diameter (ODD), and optic cup area (OCA)were measured at 33-34 weeks gestational age. As serial cranial ultrasonography had been performed, it was possible to date the brain injury in those infants with periventricular white matter (PVWM) damage.

Item Type:	Article
Additional Information:	The definitive version is available at www.blackwell-synergy.com http://group.bmj.com/
Keywords:	RetCam; image analysis; optic disc; morphology; ischaemic brain injury;
Academic Unit:	Faculty of Science and Engineering > Electronic Engineering
Item ID:	936
Depositing User:	Sean McLoone
Date Deposited:	08 Apr 2008
Journal or Publication Title:	British Journal of Ophthalmology
Publisher:	BJM Publishing
Refereed:	Yes
URI:	http://bjo.bmj.com/
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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