This article is focused on Angelo Poliziano's general attitude as a discipline and on his specific accounts of scholastic philosophy, mainly in his four opening lectures to his courses on Aristotle's ics that were held in the Florentine Studium between 1490 and 1494, in the light of his overall exclusive classical approach. It shows, among other things, that philosophy was more important to Poliziano than common expressions such as "the humanist interest in philosophy" may suggest. Poliziano's impor tant definition of history presented in his Panepistemon, together with other pieces of evidence, can reveal the moment in which disciplines associated with the "humanities" (in the modern sense of this term) began to be separated from the natural sciences — at a point just preceding the massive critique of Aristotelian science during the sixteenth century — through Poliziano's notion of a philosophical literature to which also the Aristotelian texts belong