The paper begins with explaining why there is a problem in Health, while acknowledging the major progress made in the past two centuries. The paper then identifies a fundamental problem with the current theory of the business in Health before introducing and proposing a new proactive digital paradigm Stay Left, Shift Left-10X (SL2-10X) for Health. The paper then introduces a number of Copernican shifts underpinning SL2-10X and shares a vision of a future health and wellness system. The paper then provides emerging empirical evidence for SL2-10X and explains theoretically how SL2-10X can help create more sustainable health systems through the use of an illustrative Productivity Possibility Function (PPF). Finally, an implementation strategy and potential barriers and solutions are discussed.