Constraining sea level at the Last Glacial Maximum (LGM) is spatially restricted to a few locations. Here, we reconstruct relative sea-level (RSL) changes along the Atlantic coast of Africa for the last ~30 ka BP using 347 quality-controlled sea-level datapoints. Data from the continental shelves of Guinea Conakry and Cameroon indicate a progressive lowering of RSL during the LGM from −99.4 ± 5.2 m to −104.0 ± 3.2 m between ~26.7 ka and ~19.1 ka BP. From ~15 ka to ~7.5 ka BP, RSL shows phases of major accelerations up to ~25 mm a−1 and a significant RSL deceleration by ~8 ka BP. In the mid to late Holocene, data indicate the emergence of a sea-level highstand, which varied in magnitude (0.8 ± 0.8 m to 4.0 ± 2.4 m above present mean sea level) and timing (5.0 ± 1.0 to 1.7 ± 1.0 ka BP). We further identified misfits between glacial isostatic adjustment models and the highstand, suggesting the interplay of different ice-sheet meltwater contributions and hydro-isostatic processes along the wide region of Atlantic Africa are not fully resolved.