Coogan, Andrew and Thome, Johannes (2012) Editorial: Special Issue: circadian rhythms, clock genes and neuropsychiatry: interesting times. Journal of Neural Transmission, 119 (10). pp. 1059-1060. ISSN 0300-9564
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Abstract
Circadian rhythms are cycles in physiological, behavioural,
psychological and other domains that recur approximately
every 24 h. Such rhythms are driven by an endogenous
circadian timekeeping system, whose molecular basis
consists of the interlocking transcription and translation of
a panel of "clock" genes, the expression of which then
regulates gene expression and cellular function in a tissuespecific
manner. Such rhythmic expression of clock genes
is observed in most tissues, including the master circadian
pacemaker in the suprachiasmatic nucleus of the hypothalamus,
other CNS sites and peripheral organs. Therefore,
the circadian system exerts considerable control over
physiology and behaviour, and equally dysfunction of this
circadian system may result in detrimental pathophysiological
and psychopathological consequences.
Item Type: | Article |
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Additional Information: | The definitive version of this article is available at DOI 10.1007/s00702-012-0891-y |
Keywords: | circadian rhythms; clock genes; neuropsychiatry; |
Academic Unit: | Faculty of Science and Engineering > Psychology |
Item ID: | 4153 |
Depositing User: | Dr. Andrew Coogan |
Date Deposited: | 30 Jan 2013 16:55 |
Journal or Publication Title: | Journal of Neural Transmission |
Publisher: | Springer Verlag |
Refereed: | Yes |
Related URLs: | |
URI: | https://mural.maynoothuniversity.ie/id/eprint/4153 |
Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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