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Gavin, Declan P. and Stephens, John C. (2013) Selective Michael additions to alkylidenemalonates using thiourea-based bifunctional organocatalysts. Arkivoc, 4. pp. 76-87. ISSN 1551-7012
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Abstract
Bifunctional thiourea catalysts have been found to be excellent promoters of the challenging Michael addition to alkylidenemalonates giving high yields of up to 99%. Substrate structure was important for enantiodiscrimination, with aryl alkylidenemalonate acceptors furnishing products with ee values of up to 73%.
| Item Type: | Article |
|---|---|
| Additional Information: | Published under a Creative Commons Attribution Non-Commercial License |
| Keywords: | Organocatalysis; alkylidenemalonates; β-diketones; nitromethane; Michael addition; bifunctional thiourea catalysts; |
| Academic Unit: | Faculty of Science and Engineering > Chemistry |
| Item ID: | 6335 |
| Depositing User: | Dr John Stephens |
| Date Deposited: | 07 Sep 2015 09:13 |
| Journal or Publication Title: | Arkivoc |
| Publisher: | Arkat USA Inc. |
| Refereed: | Yes |
| Related URLs: | |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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