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McKiernan, Margaret T. and Heaney, Frances (1996) Chemoselective formation of symmetrically linked bisisoxazole units: steps toward isoxazoline/isoxazolidine based macrocycles. Tetrahedron Letters, 37 (26). pp. 4597-4600. ISSN 0040-4039
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Abstract
Symmetrically linked bisisoxazole derivatives can be formed from a chemselective one-pot three component reaction between oximes, dipole generating and dipole trapping components. The use of bifunctional dipole generating moieties affords bisisoxazolines (11), linked through their N-atoms. The employment of bifunctional dipolarophilic agents leads to bisisoxazolidines (3 and 4) linked via their C-5 carbon atoms.
| Item Type: | Article |
|---|---|
| Keywords: | Chemoselective formation; symmetrically linked bisisoxazole units; isoxazoline/isoxazolidine; macrocycles; |
| Academic Unit: | Faculty of Science and Engineering > Chemistry |
| Item ID: | 7965 |
| Identification Number: | 10.1016/0040-4039(96)00886-6 |
| Depositing User: | Dr. Frances Heaney |
| Date Deposited: | 24 Feb 2017 16:32 |
| Journal or Publication Title: | Tetrahedron Letters |
| Publisher: | Elsevier |
| Refereed: | Yes |
| Funders: | Forbairt |
| Related URLs: | |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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