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Heaney, Frances and Bourke, Sharon (1995) The synthesis of 1,2,7,11b-Tetrahydroisoxazolo[2,3-d][1,4]benzodiazepin-6(5H)-ones and 1,3,3a,9b-tetrahydroisoxazolo[4,3-c]quinolin-4(5H)-ones. Tetrahedron Letters, 36 (41). pp. 7527-7530. ISSN 0040-4039
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Abstract
The reaction of various ethyl 3-[[2-(1-hydroxyiminoalkyl)phenyl]carbamoyl]acrylates (2) with electron deficient olefins proceeds via a sequential dipole formation, dipolar cycloaddition sequence to furnish the tetrahydroisoxazolo[2,3-d][1,4]benzodiazepin-6(5H)-ones and tetrahydroisoxazolo[4,3-c]quinolin-4(5H)-ones (4) and (6). The product distribution reflects the nature of the reacting olefin and the position and extent of substitution on the acrylate moiety.
| Item Type: | Article |
|---|---|
| Keywords: | synthesis; 1,2,7,11b-Tetrahydroisoxazolo[2,3-d][1,4]benzodiazepin-6(5H)-ones; 1,3,3a,9b-tetrahydroisoxazolo[4,3-c]quinolin-4(5H)-ones; ethyl 3-[[2-(1-hydroxyiminoalkyl)phenyl]carbamoyl]acrylates; |
| Academic Unit: | Faculty of Science and Engineering > Chemistry |
| Item ID: | 7970 |
| Identification Number: | 10.1016/0040-4039(95)01523-X |
| Depositing User: | Dr. Frances Heaney |
| Date Deposited: | 24 Feb 2017 16:30 |
| Journal or Publication Title: | Tetrahedron Letters |
| Publisher: | Elsevier |
| Refereed: | Yes |
| Related URLs: | |
| URI: | https://mural.maynoothuniversity.ie/id/eprint/7970 |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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