Article

Evans, Clara, Ahmed, Muhib, Beirne, Darren F., McCann, Malachy, Kavanagh, Kevin, Devereux, Michael, Rooney, Denise and Heaney, Frances (2023) Synthesis, characterisation, and solution behaviour of Ag(I) bis(phenanthroline-oxazine) complexes and the evaluation of their biological activity against the pathogenic yeast Candida albicans. Biometals, 36 (6). pp. 1241-1256. ISSN 0966-0844

Ahmed, Muhib, Ward, Sinead, McCann, Malachy, Kavanagh, Kevin, Heaney, Frances, Devereux, Michael, Twamley, Brendan and Rooney, Denise (2022) Synthesis and characterisation of phenanthroline-oxazine ligands and their Ag(I), Mn(II) and Cu(II) complexes and their evaluation as antibacterial agents. BioMetals, 35 (1). pp. 173-185. ISSN 0966-0844

O’Keeffe, Muireann, Crehan, Martina, Munro, Morag, Logan, Anna, Farrell, Ann Marie, Clarke, Eric, Flood, Michelle, Ward, Monica, Andreeva, Tatiana, Van Egeraat, Chris, Heaney, Frances, Curran, Declan and Clinton, Eric (2021) Exploring the role of peer observation of teaching in facilitating cross-institutional professional conversations about teaching and learning. International Journal for Academic Development, 26 (3). pp. 266-278. ISSN 1360-144X

O'Sullivan, Justine, Colleran, John, Twamley, Brendan and Heaney, Frances (2019) Highly Selective Fluorimetric Turn-Off Detection of Copper(II) by Two Different Mechanisms in Calix[4]arene-Based Chemosensors and Chemodosimeters. ChemPlusChem, 84 (10). pp. 1610-1622. ISSN 2192-6506

Maher, Niall, Diao, Haowen, O'Sullivan, Justine, Fadda, Elisa, Heaney, Frances and McGinley, John (2015) Lower rim isoxazole-calix[4]arene derivatives as fluorescence sensors for copper(II) ions. Tetrahedron, 71 (49). pp. 9223-9233. ISSN 0040-4020

Algay, Virginie, O'Sullivan, Justine and Heaney, Frances (2014) C-3β-Tethered Functional Cholesterol Conjugates by Nitrile Oxide Alkyne Cycloaddition (NOAC). European Journal of Organic Chemistry, 2014 (12). pp. 2522-2532. ISSN 1434-193X

Freeman, Colin, Vyle, Joseph S. and Heaney, Frances (2013) Oligo switches: photoresponsive oligonucleotide conjugates by solid-supported click chemistry. RSC Advances, 3. pp. 1652-1655. ISSN 2046-2069

Singh, Ishwar , Freeman, Colin, Madder, Annemieke, Vyle, Joseph S. and Heaney, Frances (2012) Fast RNA conjugations on solid phase by strain-promoted cycloadditions. Organic & Biomolecular Chemistry, 10 (33). pp. 6633-6639. ISSN 1477-0520

Heaney, Frances (2012) Nitrile Oxide/Alkyne Cycloadditions – A Credible Platform for Synthesis of Bioinspired Molecules by Metal-Free Molecular Clicking. European Journal of Organic Chemistry, 16. pp. 3043-3058. ISSN 1434-193X

Freeman, Colin, Ni Cheallaigh, Aisling and Heaney, Frances (2011) Conjugation at the oligonucleotide level based on isoxazole phosphoramidites generated by click chemistry. Tetrahedron, 67 (40). pp. 7860-7865. ISSN 0040-4020

Singh, Ishwar, Freeman, Colin and Heaney, Frances (2011) Efficient Synthesis of DNA Conjugates by Strain-Promoted Azide–Cyclooctyne Cycloaddition in the Solid Phase. European Journal of Organic Chemistry, 33. pp. 6739-6746. ISSN 1434-193X

Doyle, Linda and Heaney, Frances (2011) NH-Isoxazolo-bicycles; new molecular scaffolds for organocatalysis. Tetrahedron, 67 (11). pp. 2132-2138. ISSN 0040-4020

Singh, Ishwar , Zarafshani, Zoya, Heaney, Frances and Lutz, Jean-François (2011) Orthogonal modification of polymer chain-ends via sequential nitrile oxide–alkyne and azide–alkyne Huisgen cycloadditions. Ploymer Chemistry, 2. pp. 372-375. ISSN 1759-9954

Singh, Ishwar and Heaney, Frances (2011) Solid phase strain promoted “click” modification of DNA via [3+2]-nitrile oxide–cyclooctyne cycloadditions. Chemical Communications, 47. pp. 2706-2708. ISSN 1359-7345

Doyle, Linda and Heaney, Frances (2010) An investigation of structure-reactivity relationships of d-alkenyl oximes; competitive thermal reactions leading to cyclic nitrones and/or N-unsubstituted bicyclic isoxazolidines. Tetrahedron, 66. pp. 7041-7049. ISSN 0040-4020

Singh, Ishwar and Heaney, Frances (2010) Metal free, “click and click–click” conjugation of ribonucleosides and 2′-OMe oligoribonucleotides on the solid phase. Organic & Biomolecular Chemistry, 8 (3). pp. 451-456. ISSN 1477-0520

Algay, Virginie, Singh, Ishwar and Heaney, Frances (2010) Nucleoside and nucleotide analogues by catalyst free Huisgen nitrile oxide–alkyne 1,3-dipolar cycloaddition. Organic & Biomolecular Chemistry, 8. pp. 391-397. ISSN 1477-0520

Singh, Ishwar, Vyle, Joseph S. and Heaney, Frances (2009) Fast, copper-free click chemistry: a convenient solid-phase approach to oligonucleotide conjugation. Chemical Communications (22). pp. 3276-3278. ISSN 1359-7345

Singh, Ishwar, Zarafshani, Zoya, Lutz, Jean-François and Heaney, Frances (2009) Metal-Free “Click” Chemistry: Efficient Polymer Modification via 1,3-Dipolar Cycloaddition of Nitrile Oxides and Alkynes. Macromolecules, 42 (15). pp. 5411-5413. ISSN 0024-9297

Heaney, Frances and Lawless, Elaine (2007) 2-vinyl quinazoline 3-oxides; preparation from acid induced cyclocondensation of 2-acylaminoaryloximes. Journal of Heterocyclic Chemistry, 44. pp. 569-574. ISSN 0022-152X

Heaney, Frances, Lawless, Elaine, Mahon, Mary, McArdle, Patrick and Cunningham, Desmond (2006) 1,3-Dipolar character of 2-vinyl quinazoline 3-oxides; first and second generation cycloaddition products. Organic and Biomolecular Chemistry, 4 (12). pp. 2408-2416. ISSN 1477-0520

Heaney, Frances, McCarthy, Tomas, Mahon, Mary and McKee, V. (2005) Bridgehead nitrogen heterocycles which contain the quinazoline moiety – synthesis and cycloaddition of 1,2-dihydroquinazoline 3-oxides. Organic & Biomolecular Chemistry, 3. pp. 4351-4361. ISSN 1477-0520

Heaney, Frances, O'Mahony, Colm, McArdle, Patrick and Cunningham, Desmond (2003) Isoxazolo[2,3-d][1,4]benzoxazepine rings from 1,3-dipolar cycloaddition of [1,4]benzoxazepine N-oxides with acetylenic and olefinic dipolarophiles. Arkivoc, 7. pp. 161-179. ISSN 1551-7012

Heaney, Frances, Fenlon, Julie, McArdle, Patrick and Cunningham, Desmond (2003) α-Keto amides as precursors to heterocycles—generation and cycloaddition reactions of piperazin-5-one nitrones. Organic and Biomolecular Chemistry, 1 (7). pp. 1122-1132. ISSN 1477-0520

Heaney, Frances, Fenlon, Julie, O'Mahony, Colm, McArdle, Patrick and Cunningham, Desmond (2003) α-Oximono-esters as precursors to heterocycles – generation of oxazinone N-oxides and cycloaddition to alkene dipolarophiles. Organic and Biomolecular Chemistry, 1 (23). pp. 4302-4316. ISSN 1477-0520

Heaney, Frances, Fenlon, Julie, O'Mahony, Colm, McArdle, Patrick and Cunningham, Desmond (2001) Nitrogen-containing heterocycles: 1,3-dipolar cycloaddition of stabilized nitrones with alkynes; primary cycloadducts, first and second generation rearrangement processes. Journal of the Chemical Society, Perkin Tranactions 1, 1 (24). pp. 3382-3392. ISSN 0300-922X

Heaney, Frances, Burke, Cathriona, Cunningham, Desmond and McArdle, Patrick (2001) Pyrimidine annelated heterocycles—synthesis and cycloaddition of the first pyrimido[1,4]diazepine N-oxides. Journal of the Chemical Society, Perkin Transactions 1 (6). pp. 622-632. ISSN 0300-922X

Heaney, Frances, Rooney, Oliver, Cunningham, Desmond and McArdle, Patrick (2001) Simultaneous double 1,3-dipolar cycloaddition reactions involving bisnitrones or bisdipolarophiles. 1H NMR investigation of the conformational preferences of N-methyl- and N-phenylisoxazolidines. Journal of the Chemical Society, Perkin Transactions 2, 2001 (3). pp. 373-378. ISSN 1472-779X

Heaney, Frances, Kelly, Bronwyn M., Bourke, Sharon, Rooney, Oliver, Cunningham, Desmond and McArdle, Patrick (1999) Site selectivity in the addition of ketoximes to activated allenes and alkynes; N- versus O-alkylation. Journal of the Chemical Society, Perkin Transactions 1, 1. pp. 143-148. ISSN 0300-922X

Heaney, Frances and Bourke, Sharon (1998) Nitrogen containing heterocycles from aldoximes; a one-pot route to isoxazolobenzodiazepinones, N-substituted and N-unsubstituted isoxazoloquinolinones. Journal of the Chemical Society, Perkin Translations 1, 1 (5). pp. 955-964. ISSN 0300-922X

Heaney, Frances, Bourke, Sharon, Burke, Cathriona, Cunningham, Desmond and McArdle, Patrick (1998) Preparation of imidazo[1,2-c]pyrimidinones from a chloropyrimidine and an electron poor ω-allylic amine. Journal of the Chemical Society, Perkin Transactions 1, 1. pp. 2255-2258. ISSN 0300-922X

Heaney, Frances, Bourke, Sharon, Cunningham, Desmond and McArdle, Patrick (1998) Steric control of reactivity: formation of oximes, benzodiazepinone N-oxides and isoxazoloquinolinones. Journal of the Chemical Society, Perkin Transactions 2, 1998 (3). pp. 547-560. ISSN 1472-779X

Heaney, Frances and O'Mahony, Colm (1998) The influence of oxime stereochemistry in the generation of nitrones from ω-alkenyloximes by cyclization or 1,2-prototropy. Journal of the Chemical Society, Perkin Transactions 1, 1998 (2). pp. 341-350. ISSN 0300-922X

McKiernan, Margaret T. and Heaney, Frances (1996) Chemoselective formation of symmetrically linked bisisoxazole units: steps toward isoxazoline​/isoxazolidine based macrocycles. Tetrahedron Letters, 37 (26). pp. 4597-4600. ISSN 0040-4039

Heaney, Frances and Bourke, Sharon (1995) The synthesis of 1,2,7,11b-Tetrahydroisoxazolo[2,3-d][1,4]benzodiazepin-6(5H)-ones and 1,3,3a,9b-tetrahydroisoxazolo[4,3-c]quinolin-4(5H)-ones. Tetrahedron Letters, 36 (41). pp. 7527-7530. ISSN 0040-4039

Monograph

Singh, Ishwar , Vyle, Joseph S. and Heaney, Frances (2009) Supporting Information: Fast, Copper-Free Click Chemistry, A Convenient Solid-Phase Approach to Oligonucleotide Conjugation. Documentation. Royal Society of Chemistry.