2009

Krippendorff, Ben-Fillippo, Neuhaus, Roland, Lienau, Philip, Reichel, Andreas and Huisinga, Wilhelm (2009) Mechanism-based Inhibition: Deriving KI and kinact directly from Time-Dependent IC50 Values. Journal of Biomedical Screening, 14 (8). pp. 913-923. ISSN 1087-0571

Krippendorff, Ben-Fillippo, Kuester, Katharina, Kloft, Charlotte and Huisinga, Wilhelm (2009) Nonlinear pharmacokinetics of therapeutic proteins resulting from receptor mediated endocytosis. Journal of Pharmacokinetics and Pharmacodynamics , 36 (3). pp. 239-260. ISSN 1567-567X

Krippendorff, Ben-Fillippo, Oyarzun, Diego and Huisinga, Wilhelm (2009) Ligand accumulation counteracts therapeutic inhibition of receptor systems. In: Third International Conference on Foundations of Systems Biology in Engineering (FOSBE 2009), August 9-12 2009, Denver, Colorado. (Unpublished)

von Kleist, Max and Huisinga, Wilhelm (2009) Pharmacokinetic-Pharmacodynamic relationship of NRTIs and its connection to viral escape: An example based on Zidovudine. European Journal of Pharmaceutical Sciences, 36 (4-5). pp. 535-543. ISSN 0928-0987

2007

von Kleist, Max and Huisinga, Wilhelm (2007) Physiologically Based Pharmacokinetic Modelling: A Sub-Compartmentalized Model of Tissue Distribution. Journal of Pharmacokinetics and Pharmacodynamics, 34 (6). pp. 789-806. ISSN 1573-8744

Krippendorff, Ben-Fillippo, Lienau, Philip , Reichel, Andreas and Huisinga, Wilhelm (2007) Optimizing Classification of Drug-Drug Interaction Potential for CYP450 Iso-Enzymes Inhibition Assays in Early Drug Discovery. Journal of Biomolecular Screening, 12 (1). pp. 92-99. ISSN 1087-0571

Jahnke, Tobias and Huisinga, Wilhelm (2007) Solving the chemical master equation for monomolecular reaction systems analytically. Journal of Mathematical Biology. ISSN 1432-1416

2006

Huisinga, Wilhelm, Telgmann, Regina and Wulkow, Michael (2006) The Virtual Lab Approach to Pharmacokinetics: Design Principles and Concepts. Drugs Discovery Today, 11 (17-18). pp. 773-862. ISSN 1359-6446

Huisinga, Wilhelm (2006) Computational Physiology. European Communications in Mathematical and Theoretical Biology (8). pp. 12-13.

Weiße, Andrea Y., Horenko, Illia and Huisinga, Wilhelm (2006) Adaptive Approach for Modelling Variability in Pharmacokinetics. In: Computational Life Sciences II Second International Symposium, CompLife 2006 Cambridge, UK, September 27-29, 2006. Proceedings. Lecture Notes in Computer Science (LNCS), 4216/2006 . Springer Berlin / Heidelberg, pp. 194-204. ISBN 978-3-540-45767-1

Telgmann, Regina , von Kleist, Max and Huisinga, Wilhelm (2006) Software supported modelling in pharmacokinetics. In: Computational Life Sciences II: Second International Symposium, CompLife 2006, Cambridge, UK, September 27-29, 2006. Proceedings. Lecture Notes in Computer Science (LNCS), 4216/2006 . Springer Berlin / Heidelberg, pp. 216-225. ISBN 978-3-540-45767-1

2005

Alfonsi, Aurélien, Cancès, Eric, Turinici, Gabriel, Di Ventura, Barbara and Huisinga, Wilhelm (2005) Adaptive simulation of hybrid stochastic and deterministic models for biochemical systems. ESAIM: Proceedings, 14 (September). pp. 1-13. ISSN 1270-900X

Horenko, Illia, Lorenz, Sönke, Schütte, Christof and Huisinga, Wilhelm (2005) Adaptive approach for non-linear sensitivity analysis of reaction kinetics. Journal of Computational Chemistry, 26 (9). pp. 941-948. ISSN 0192-8651

Abraham, Klaus, Mielke, Hans, Huisinga, Wilhelm and Gundert-Remy, Ursula (2005) Elevated Internal Exposure of Children in Simulated Acute Inhalation of Volatile Organic Compounds: Effects of Concentration and Duration. Archives of Toxicology, 79 (2). pp. 63-73. ISSN 1432-0738