Article

Dunbar, Hazel, Hawthorne, Ian J., Tunstead, Courteney, McNamee, Eóin N., Weiss, Daniel J., Armstrong, Michelle E., Donnelly, Seamas C. and English, Karen (2024) Mesenchymal stromal cells dampen trained immunity in house dust mite-primed macrophages expressing human macrophage migration inhibitory factor polymorphism. Cytotherapy, 26 (10). pp. 1245-1251. ISSN 1465-3249

Dunbar, Hazel, Hawthorne, Ian J., McNamee, Eóin N., Armstrong, Michelle E., Donnelly, Seamas C. and English, Karen (2024) The human MIF polymorphism CATT7 enhances pro‐inflammatory macrophage polarization in a clinically relevant model of allergic airway inflammation. The FASEB Journal, 38 (6). ISSN 0892-6638

Masterson, Joanne C., Biette, K.A., Hammer, J.A., Nguyen, Nathalie, Capocelli, Kelley E., Saeedi, Bejan J., Harris, Rachel F., Fernando, Shahan D., Hosford, Lindsay, Kelly, Caleb J., Campbell, Eric L., Ehrentraut, Stefan F., Ahmed, Faria N., Nakagawa, Hiroshi, Lee, James J., McNamee, Eóin N., Glover, Louise, Colgan, S.P. and Furuta, Glenn T. (2019) Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis. The Journal of Clinical Investigation, 129 (8). pp. 3224-3235. ISSN 0021-9738

McNamee, Eóin N. (2019) Neutrophil-derived microRNAs put the (DNA) breaks on intestinal mucosal healing. Journal of Clinical Investigation, 129 (2). pp. 499-502. ISSN 1558-8238

Jones, Jennifer C., Brindley, Constance D., Elder, Nicholas H., Myers, Martin G., Rajala, Michael W., Dekaney, Christopher M., McNamee, Eóin N., Frey, Mark R., Shroyer, Noah F. and Dempsey, Peter J. (2018) Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cellular and Molecular Gastroenterology and Hepatology, 7 (3). ISSN 2352-345X

McNamee, Eóin N. and Rivera-Nieves, Jesus (2017) Defective Lymphatics in Crohn’s Disease: Tertiary Lymphoid Follicles Plug the Gap. Gastroenterology, 152 (4). pp. 908-910. ISSN 0016-5085

Hoegl, Sandra, Ehrentraut, Heidi, Brodsky, Kelley S., Victorino, Francisco, Golden‐Mason, Lucy, Eltzschig, Holger K. and McNamee, Eóin N. (2017) NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury. Journal of Leukocyte Biology, 101. pp. 471-480. ISSN 0741-5400

Neudecker, Viola, Haneklaus, Moritz, Jensen, Owen, Khailova, Ludmila, Masterson, Joanne C., Tye, Hazel, Biette, K.A., Jedlicka, Paul, Brodsky, Kelley S., Gerich, Mark E., Mack, Matthias, Robertson, Avril A.B, Cooper, Matthew A., Furuta, Glenn T., Dinarello, Charles A., O’Neill, Luke A., Eltzschig, Holger K., Masters, Seth L. and McNamee, Eóin N. (2017) Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. Journal of Experimental Medicine, 214 (6). p. 1737. ISSN 0022-1007

McNamee, Eóin N., Biette, K.A., Hammer, J.A., Harris, R., Miyazawa, H., Lee, James J., Furuta, Glenn T. and Masterson, Joanne C. (2017) Targeting granulocyte‐macrophage colony‐stimulating factor in epithelial and vascular remodeling in experimental eosinophilic esophagitis. Allergy, 72. pp. 1232-1242. ISSN 1398-9995

Ryan, Karen M., Griffin, Éadaoin W., Ryan, Katie J., Tanveer, Riffat, Vanattou-Saifoudine, Natacha, McNamee, Eóin N., Fallon, Emer, Heffernan, Sheena, Harkin, Andrew and Connor, Thomas J. (2016) Clenbuterol activates the central IL-1 system via the b2-adrenoceptor without provoking inflammatory response related behaviours in rats. Brain, Behavior, and Immunity, 56. pp. 114-129. ISSN 0889-1591

McNamee, Eóin N. and Rivera-Nieves, Jesus (2016) Ectopic Tertiary Lymphoid Tissue in Inflammatory Bowel Disease: Protective or Provocateur? Frontiers in Immunology, 7. ISSN 1664-3224

Frasch, S. Courtney, McNamee, Eóin N., Kominsky, Douglas J., Jedlicka, Paul, Jakubzick, Claudia, Berry, Karin Zemski, Mack, Matthias, Furuta, Glenn T., Lee, James J., Henson, Peter M., Colgan, S.P. and Bratton, Donna L. (2016) G2A Signaling Dampens Colitic Inflammation via Production of IFN-γ. Journal of Immunology, 197. pp. 1425-1434. ISSN 0022-1767

Ferrari, Davide, McNamee, Eóin N., Idzko, Marco, Gambari, Roberto and Eltzschig, Holger K. (2016) Purinergic Signaling During Immune Cell Trafficking. Trends in Immunology, 37 (6). pp. 399-411. ISSN 1471-4906

Henry, Curtis J., Casás-Selves, Matias, Kim, Jihye, Zaberezhnyy, Vadym, Aghili, Leila, Daniel, Ashley E., Jimenez, Linda, Azam, Tania, McNamee, Eóin N., Clambey, Eric T., Klawitter, Jelena, Serkova, Natalie J., Tan, Aik Choon, Dinarello, Charles A. and DeGregori, James (2015) Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. Journal of Clinical Investigation, 125 (12). pp. 4666-4680. ISSN 1558-8238

McNamee, Eóin N., Masterson, Joanne C., Veny, Marisol, Collins, Colm B., Jedlicka, Paul, Byrne, Fergus R., Ng, Gordon Y. and Rivera-Nieves, Jesus (2015) Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn’s-like murine ileitis. Journal Of Leukocyte Biology, 97 (6). pp. 1011-1022. ISSN 1938-3673

Masterson, Joanne C., McNamee, Eóin N., Fillon, Sophie A., Hosford, Lindsay, Harris, Rachel, Fernando, Shahan D., Jedlicka, Paul, Iwamoto, Ryo, Jacobsen, Elizabeth A., Protheroe, Cheryl, Eltzschig, Holger K., Colgan, S.P., Makoto, Arita, Lee, James J. and Furuta, Glenn T. (2015) Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis. Gut, 64 (8). pp. 1236-1247. ISSN 1468-3288

Masterson, Joanne C., Capocelli, Kelley E., Hosford, Lindsay, Biette, K.A., McNamee, Eóin N., de Zoeten, Edwin F., Harris, Rachel, Fernando, Shahan D., Jedicka, Paul, Protheroe, Cheryl, Lee, James J. and Furuta, Glenn T. (2015) Eosinophils and IL-33 Perpetuate Chronic Inflammation and Fibrosis in a Pediatric Population with Stricturing Crohn’s Ileitis. Inflammatory Bowel Diseases, 21 (10). pp. 2429-2440. ISSN 1536-4844

Aherne, Carole M., Saeedi, B., Collins, C.B., Masterson, Joanne C., McNamee, Eóin N., Perrenoud, L., Rapp, C.R., Curtis, V.F., Bayless, A., Fletcher, A., Glover, L.E., Evans, C.M., Jedlicka, Paul, Furuta, Glenn T., de Zoeten, Edwin F., Colgan, S.P. and Eltzschig, Holger K. (2015) Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal immunology, 8 (6). pp. 1324-1338. ISSN 1935-3456

Victorino, Francisco, Sojka, Dorothy K., Brodsky, Kelley S., McNamee, Eóin N., Masterson, Joanne C., Homann, Dirk, Yokoyama, Wayne M., Eltzschig, Holger K. and Clambey, Eric T. (2015) Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody. Journal of Immunology, 195 (10). pp. 4973-4985. ISSN 0022-1767

Keely, S., Campbell, E.L., Baird, A.W., Hansbro, P.M., Shalwitz, R.A., Kotsakis, A., McNamee, Eóin N., Eltzschig, Holger K., Kominsky, Douglas J. and Colgan, S.P. (2014) Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis. Mucosal immunology, 7 (1). pp. 114-123. ISSN 1935-3456

Masterson, Joanne C., McNamee, Eóin N., Hosford, Lindsay, Capocelli, Kelley E., Ruybal, Joseph, Fillon, Sophie A., Doyle, Alfred D., Eltzschig, Holger K., Rustgi, Anil K., Protheroe, Cheryl, Lee, Nancy A., Lee, James J. and Furuta, Glenn T. (2014) Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis. Gut, 63 (1). pp. 43-53. ISSN 1468-3288

Campbell, Eric L., Bruyninckx, Walter J., Kelly, Caleb J., Glover, Louise, McNamee, Eóin N., Bowers, Brittelle E., Bayless, Amanda J., Scully, Melanie, Saeedi, Bejan J., Golden-Mason, Lucy, Ehrentraut, Stefan F., Curtis, Valerie F., Burgess, Adrianne, Garvey, John F., Sorensen, Amber, Nemenoff, Raphael, Jedlicka, Paul, Taylor, Cormac T, Kominsky, Douglas J and Colgan, S.P. (2014) Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation. Immunity, 40 (1). pp. 66-77. ISSN 1097-4180

Collins, Colm B., Aherne, Carol M., Ehrentraut, Stefan F., Gerich, Mark E., McNamee, Eóin N., McManus, Martine, Lebsack, Matthew D.P., Jedlicka, Paul, Azam, Tania, de Zoeten, Edwin F., Dinarello, Charles A. and Rivera-Nieves, Jesus (2013) Alpha-1-antitrypsin Therapy Ameliorates Acute Colitis and Chronic Murine Ileitis. Inflammatory Bowel Diseases, 19 (9). pp. 1964-1973. ISSN 1536-4844

Ehrentraut, Heidi, Clambey, Eric T., McNamee, Eóin N., Brodsky, Kelley S., Ehrentraut, Stefan F., Poth, Jens M., Riegel, Ann K., Westrich, Joseph A., Colgan, S.P. and Eltzschig, Holger K. (2013) CD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury. FASEB Journal, 27 (6). pp. 2207-2219. ISSN 1530-6860

Koeppen, M, McNamee, Eóin N., Brodsky, Kelley S., Aherne, Carol M., Faigle, M, Downey, GP, Colgan, S.P., Evans, CM, Schwartz, DA and Eltzschig, Holger K. (2013) Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury. Immunologic Research, 55 (1-3). pp. 762-775. ISSN 1559-0755

McNamee, Eóin N., Masterson, Joanne C., Jedlicka, Paul, Collins, Colm B., Williams, Ifor R. and Rivera-Nieves, Jesus (2013) Ectopic lymphoid tissue alters the chemokine gradient, increases lymphocyte retention and exacerbates murine ileitis. Gut, 62 (1). pp. 53-62. ISSN 1468-3288

McNamee, Eóin N., Korns Johnson, Darlynn, Homann, Dirk and Clambey, Eric T. (2013) Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function. Immunologic Research, 55 (1-3). pp. 58-70. ISSN 1559-0755

Khailova, Ludmila, Baird, Christine H., Rush, Aubri A., McNamee, Eóin N. and Wischmeyer, Paul E. (2013) Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. Shock, 40 (6). pp. 496-503. ISSN 1073-2322

Ryan, Katie J., Griffin, Éadaoin, Yssel, Justin D., Ryan, Karen M., McNamee, Eóin N., Harkin, Andrew and Connor, Thomas J. (2013) Stimulation of central β2-adrenoceptors suppresses NFκB activity in rat brain: a role for IκB. Neurochemistry International, 63 (5). ISSN 1872-9754

Collins, Colm B., Aherne, Carol M., McNamee, Eóin N., Lebsack, Matthew D.P., Eltzschig, Holger K., Jedlicka, Paul and Rivera-Nieves, Jesus (2012) Flt3 ligand expands CD103+ dendritic cells and FoxP3+ T regulatory cells, and attenuates Crohn’s-like murine ileitis. Gut, 61 (8). pp. 1154-1162. ISSN 1468-3288

Clambey, Eric T., McNamee, Eóin N., Westrich, Joseph A., Glover, Louise, Campbell, Eric L., Jedlicka, Paul, de Zoeten, Edwin F., Cambier, John C., Stenmark, Kurt R., Colgan, S.P. and Eltzschig, Holger K. (2012) Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proceedings of the National Academy of Sciences of the United States of America, 109 (41). E2784-E2793. ISSN 0027-8424

Masterson, Joanne C., McNamee, Eóin N., Jedlicka, Paul, Fillon, Sophie A., Ruybal, Joseph, Hosford, Lindsay, Rivera-Nieves, Jesus, Lee, James J. and Furuta, Glenn T. (2011) CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling. American Journal of Pathology, 179 (5). pp. 2302-2314. ISSN 0002-9440

McNamee, Eóin N., Masterson, Joanne C., Jedlicka, Paul, McManus, Martine, Grenz, Almut, Collins, Colm B., Nold, Marcel F., Nold-Petry, Claudia, Bufler, Philip, Dinarello, Charles A. and Rivera-Nieves, Jesus (2011) Interleukin 37 expression protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America, 108 (40). pp. 16711-16716. ISSN 0027-8424

Wermers, Joshua D., McNamee, Eóin N., Wurbel, Marc-André, Jedlicka, Paul and Rivera-Nieves, Jesus (2011) The chemokine receptor CCR9 is required for the T cellmediated regulation of chronic ileitis in mice. Gastroenterology, 140 (5). ISSN 0016-5085

McNamee, Eóin N., Collins, Colm B., Lebsack, Matthew D.P. and Rivera-Nieves, Jesus (2010) Cell-Specific Inhibition of p38α as a Therapeutic Strategy for Inflammatory Bowel Disease. Gastroenterology, 138 (4). ISSN 0016-5085

Collins, Colm B., McNamee, Eóin N., Wermers, Joshua D., Lebsack, Matthew D.P. and Rivera-Nieves, Jesus (2010) Chemokine decoy receptor D6 in inflammatory bowel disease (IBD) and IBD-associated colon cancer. Gut, 59 (2). ISSN 1468-3288

McNamee, Eóin N., Griffin, Éadaoin W., Ryan, Karen M., Ryan, Katie J., Heffernan, Sheena, Harkin, Andrew and Connor, Thomas J. (2010) Noradrenaline acting at β-adrenoceptors induces expression of IL-1β and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex. Neuropharmacology, 59. pp. 37-48. ISSN 1873-7064

McNamee, Eóin N., Ryan, Karen M., Kilroy, Dana and Connor, Thomas J. (2010) Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1β-induced neurotoxicity. European Journal of Pharmacology, 626. pp. 219-228. ISSN 0014-2999

McNamee, Eóin N., Wermers, Joshua D., Masterson, Joanne C., Collins, Colm B., Lebsack, Matthew D.P., Fillon, Sophie A., Robinson, Zachary, Grenawalt, Joanna, Lee, James J., Jedlicka, Paul, Furuta, Glenn T. and Rivera-Nieves, Jesus (2010) A Novel Model of TH2-polarized Chronic Ileitis: The SAMP1 Mouse. Inflammatory Bowel Diseases, 16 (5). pp. 743-752. ISSN 1536-4844