Article

Masterson, Joanne C. and Biette, K.A. and Hammer, J.A. and Nguyen, Nathalie and Capocelli, Kelley E. and Saeedi, Bejan J. and Harris, Rachel F. and Fernando, Shahan D. and Hosford, Lindsay and Kelly, Caleb J. and Campbell, Eric L. and Ehrentraut, Stefan F. and Ahmed, Faria N. and Nakagawa, Hiroshi and Lee, James J. and McNamee, Eóin N. and Glover, Louise and Colgan, S.P. and Furuta, Glenn T. (2019) Epithelial HIF-1α/claudin-1 axis regulates barrier dysfunction in eosinophilic esophagitis. The Journal of Clinical Investigation, 129 (8). pp. 3224-3235. ISSN 0021-9738

McNamee, Eóin N. (2019) Neutrophil-derived microRNAs put the (DNA) breaks on intestinal mucosal healing. Journal of Clinical Investigation, 129 (2). pp. 499-502. ISSN 1558-8238

Jones, Jennifer C. and Brindley, Constance D. and Elder, Nicholas H. and Myers, Martin G. and Rajala, Michael W. and Dekaney, Christopher M. and McNamee, Eóin N. and Frey, Mark R. and Shroyer, Noah F. and Dempsey, Peter J. (2018) Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cellular and Molecular Gastroenterology and Hepatology, 7 (3). ISSN 2352-345X

McNamee, Eóin N. and Rivera-Nieves, Jesus (2017) Defective Lymphatics in Crohn’s Disease: Tertiary Lymphoid Follicles Plug the Gap. Gastroenterology, 152 (4). pp. 908-910. ISSN 0016-5085

Hoegl, Sandra and Ehrentraut, Heidi and Brodsky, Kelley S. and Victorino, Francisco and Golden‐Mason, Lucy and Eltzschig, Holger K. and McNamee, Eóin N. (2017) NK cells regulate CXCR2+ neutrophil recruitment during acute lung injury. Journal of Leukocyte Biology, 101. pp. 471-480. ISSN 0741-5400

Neudecker, Viola and Haneklaus, Moritz and Jensen, Owen and Khailova, Ludmila and Masterson, Joanne C. and Tye, Hazel and Biette, K.A. and Jedlicka, Paul and Brodsky, Kelley S. and Gerich, Mark E. and Mack, Matthias and Robertson, Avril A.B and Cooper, Matthew A. and Furuta, Glenn T. and Dinarello, Charles A. and O’Neill, Luke A. and Eltzschig, Holger K. and Masters, Seth L. and McNamee, Eóin N. (2017) Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. Journal of Experimental Medicine, 214 (6). p. 1737. ISSN 0022-1007

McNamee, Eóin N. and Biette, K.A. and Hammer, J.A. and Harris, R. and Miyazawa, H. and Lee, James J. and Furuta, Glenn T. and Masterson, Joanne C. (2017) Targeting granulocyte‐macrophage colony‐stimulating factor in epithelial and vascular remodeling in experimental eosinophilic esophagitis. Allergy, 72. pp. 1232-1242. ISSN 1398-9995

Ryan, Karen M. and Griffin, Éadaoin W. and Ryan, Katie J. and Tanveer, Riffat and Vanattou-Saifoudine, Natacha and McNamee, Eóin N. and Fallon, Emer and Heffernan, Sheena and Harkin, Andrew and Connor, Thomas J. (2016) Clenbuterol activates the central IL-1 system via the b2-adrenoceptor without provoking inflammatory response related behaviours in rats. Brain, Behavior, and Immunity, 56. pp. 114-129. ISSN 0889-1591

McNamee, Eóin N. and Rivera-Nieves, Jesus (2016) Ectopic Tertiary Lymphoid Tissue in Inflammatory Bowel Disease: Protective or Provocateur? Frontiers in Immunology, 7. ISSN 1664-3224

Frasch, S. Courtney and McNamee, Eóin N. and Kominsky, Douglas J. and Jedlicka, Paul and Jakubzick, Claudia and Berry, Karin Zemski and Mack, Matthias and Furuta, Glenn T. and Lee, James J. and Henson, Peter M. and Colgan, S.P. and Bratton, Donna L. (2016) G2A Signaling Dampens Colitic Inflammation via Production of IFN-γ. Journal of Immunology, 197. pp. 1425-1434. ISSN 0022-1767

Ferrari, Davide and McNamee, Eóin N. and Idzko, Marco and Gambari, Roberto and Eltzschig, Holger K. (2016) Purinergic Signaling During Immune Cell Trafficking. Trends in Immunology, 37 (6). pp. 399-411. ISSN 1471-4906

Henry, Curtis J. and Casás-Selves, Matias and Kim, Jihye and Zaberezhnyy, Vadym and Aghili, Leila and Daniel, Ashley E. and Jimenez, Linda and Azam, Tania and McNamee, Eóin N. and Clambey, Eric T. and Klawitter, Jelena and Serkova, Natalie J. and Tan, Aik Choon and Dinarello, Charles A. and DeGregori, James (2015) Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors. Journal of Clinical Investigation, 125 (12). pp. 4666-4680. ISSN 1558-8238

McNamee, Eóin N. and Masterson, Joanne C. and Veny, Marisol and Collins, Colm B. and Jedlicka, Paul and Byrne, Fergus R. and Ng, Gordon Y. and Rivera-Nieves, Jesus (2015) Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn’s-like murine ileitis. Journal Of Leukocyte Biology, 97 (6). pp. 1011-1022. ISSN 1938-3673

Masterson, Joanne C. and McNamee, Eóin N. and Fillon, Sophie A. and Hosford, Lindsay and Harris, Rachel and Fernando, Shahan D. and Jedlicka, Paul and Iwamoto, Ryo and Jacobsen, Elizabeth A. and Protheroe, Cheryl and Eltzschig, Holger K. and Colgan, S.P. and Makoto, Arita and Lee, James J. and Furuta, Glenn T. (2015) Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis. Gut, 64 (8). pp. 1236-1247. ISSN 1468-3288

Masterson, Joanne C. and Capocelli, Kelley E. and Hosford, Lindsay and Biette, K.A. and McNamee, Eóin N. and de Zoeten, Edwin F. and Harris, Rachel and Fernando, Shahan D. and Jedicka, Paul and Protheroe, Cheryl and Lee, James J. and Furuta, Glenn T. (2015) Eosinophils and IL-33 Perpetuate Chronic Inflammation and Fibrosis in a Pediatric Population with Stricturing Crohn’s Ileitis. Inflammatory Bowel Diseases, 21 (10). pp. 2429-2440. ISSN 1536-4844

Aherne, Carole M. and Saeedi, B. and Collins, C.B. and Masterson, Joanne C. and McNamee, Eóin N. and Perrenoud, L. and Rapp, C.R. and Curtis, V.F. and Bayless, A. and Fletcher, A. and Glover, L.E. and Evans, C.M. and Jedlicka, Paul and Furuta, Glenn T. and de Zoeten, Edwin F. and Colgan, S.P. and Eltzschig, Holger K. (2015) Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal immunology, 8 (6). pp. 1324-1338. ISSN 1935-3456

Victorino, Francisco and Sojka, Dorothy K. and Brodsky, Kelley S. and McNamee, Eóin N. and Masterson, Joanne C. and Homann, Dirk and Yokoyama, Wayne M. and Eltzschig, Holger K. and Clambey, Eric T. (2015) Tissue-Resident NK Cells Mediate Ischemic Kidney Injury and Are Not Depleted by Anti-Asialo-GM1 Antibody. Journal of Immunology, 195 (10). pp. 4973-4985. ISSN 0022-1767

Keely, S. and Campbell, E.L. and Baird, A.W. and Hansbro, P.M. and Shalwitz, R.A. and Kotsakis, A. and McNamee, Eóin N. and Eltzschig, Holger K. and Kominsky, Douglas J. and Colgan, S.P. (2014) Contribution of epithelial innate immunity to systemic protection afforded by prolyl hydroxylase inhibition in murine colitis. Mucosal immunology, 7 (1). pp. 114-123. ISSN 1935-3456

Masterson, Joanne C. and McNamee, Eóin N. and Hosford, Lindsay and Capocelli, Kelley E. and Ruybal, Joseph and Fillon, Sophie A. and Doyle, Alfred D. and Eltzschig, Holger K. and Rustgi, Anil K. and Protheroe, Cheryl and Lee, Nancy A. and Lee, James J. and Furuta, Glenn T. (2014) Local hypersensitivity reaction in transgenic mice with squamous epithelial IL-5 overexpression provides a novel model of eosinophilic oesophagitis. Gut, 63 (1). pp. 43-53. ISSN 1468-3288

Campbell, Eric L. and Bruyninckx, Walter J. and Kelly, Caleb J. and Glover, Louise and McNamee, Eóin N. and Bowers, Brittelle E. and Bayless, Amanda J. and Scully, Melanie and Saeedi, Bejan J. and Golden-Mason, Lucy and Ehrentraut, Stefan F. and Curtis, Valerie F. and Burgess, Adrianne and Garvey, John F. and Sorensen, Amber and Nemenoff, Raphael and Jedlicka, Paul and Taylor, Cormac T and Kominsky, Douglas J and Colgan, S.P. (2014) Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation. Immunity, 40 (1). pp. 66-77. ISSN 1097-4180

Collins, Colm B. and Aherne, Carol M. and Ehrentraut, Stefan F. and Gerich, Mark E. and McNamee, Eóin N. and McManus, Martine and Lebsack, Matthew D.P. and Jedlicka, Paul and Azam, Tania and de Zoeten, Edwin F. and Dinarello, Charles A. and Rivera-Nieves, Jesus (2013) Alpha-1-antitrypsin Therapy Ameliorates Acute Colitis and Chronic Murine Ileitis. Inflammatory Bowel Diseases, 19 (9). pp. 1964-1973. ISSN 1536-4844

Ehrentraut, Heidi and Clambey, Eric T. and McNamee, Eóin N. and Brodsky, Kelley S. and Ehrentraut, Stefan F. and Poth, Jens M. and Riegel, Ann K. and Westrich, Joseph A. and Colgan, S.P. and Eltzschig, Holger K. (2013) CD73+ regulatory T cells contribute to adenosine-mediated resolution of acute lung injury. FASEB Journal, 27 (6). pp. 2207-2219. ISSN 1530-6860

Koeppen, M and McNamee, Eóin N. and Brodsky, Kelley S. and Aherne, Carol M. and Faigle, M and Downey, GP and Colgan, S.P. and Evans, CM and Schwartz, DA and Eltzschig, Holger K. (2013) Detrimental role of the airway mucin Muc5ac during ventilator-induced lung injury. Immunologic Research, 55 (1-3). pp. 762-775. ISSN 1559-0755

McNamee, Eóin N. and Masterson, Joanne C. and Jedlicka, Paul and Collins, Colm B. and Williams, Ifor R. and Rivera-Nieves, Jesus (2013) Ectopic lymphoid tissue alters the chemokine gradient, increases lymphocyte retention and exacerbates murine ileitis. Gut, 62 (1). pp. 53-62. ISSN 1468-3288

McNamee, Eóin N. and Korns Johnson, Darlynn and Homann, Dirk and Clambey, Eric T. (2013) Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function. Immunologic Research, 55 (1-3). pp. 58-70. ISSN 1559-0755

Khailova, Ludmila and Baird, Christine H. and Rush, Aubri A. and McNamee, Eóin N. and Wischmeyer, Paul E. (2013) Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. Shock, 40 (6). pp. 496-503. ISSN 1073-2322

Ryan, Katie J. and Griffin, Éadaoin and Yssel, Justin D. and Ryan, Karen M. and McNamee, Eóin N. and Harkin, Andrew and Connor, Thomas J. (2013) Stimulation of central β2-adrenoceptors suppresses NFκB activity in rat brain: a role for IκB. Neurochemistry International, 63 (5). ISSN 1872-9754

Collins, Colm B. and Aherne, Carol M. and McNamee, Eóin N. and Lebsack, Matthew D.P. and Eltzschig, Holger K. and Jedlicka, Paul and Rivera-Nieves, Jesus (2012) Flt3 ligand expands CD103+ dendritic cells and FoxP3+ T regulatory cells, and attenuates Crohn’s-like murine ileitis. Gut, 61 (8). pp. 1154-1162. ISSN 1468-3288

Clambey, Eric T. and McNamee, Eóin N. and Westrich, Joseph A. and Glover, Louise and Campbell, Eric L. and Jedlicka, Paul and de Zoeten, Edwin F. and Cambier, John C. and Stenmark, Kurt R. and Colgan, S.P. and Eltzschig, Holger K. (2012) Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proceedings of the National Academy of Sciences of the United States of America, 109 (41). E2784-E2793. ISSN 0027-8424

Masterson, Joanne C. and McNamee, Eóin N. and Jedlicka, Paul and Fillon, Sophie A. and Ruybal, Joseph and Hosford, Lindsay and Rivera-Nieves, Jesus and Lee, James J. and Furuta, Glenn T. (2011) CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling. American Journal of Pathology, 179 (5). pp. 2302-2314. ISSN 0002-9440

McNamee, Eóin N. and Masterson, Joanne C. and Jedlicka, Paul and McManus, Martine and Grenz, Almut and Collins, Colm B. and Nold, Marcel F. and Nold-Petry, Claudia and Bufler, Philip and Dinarello, Charles A. and Rivera-Nieves, Jesus (2011) Interleukin 37 expression protects mice from colitis. Proceedings of the National Academy of Sciences of the United States of America, 108 (40). pp. 16711-16716. ISSN 0027-8424

Wermers, Joshua D. and McNamee, Eóin N. and Wurbel, Marc-André and Jedlicka, Paul and Rivera-Nieves, Jesus (2011) The chemokine receptor CCR9 is required for the T cellmediated regulation of chronic ileitis in mice. Gastroenterology, 140 (5). ISSN 0016-5085

McNamee, Eóin N. and Collins, Colm B. and Lebsack, Matthew D.P. and Rivera-Nieves, Jesus (2010) Cell-Specific Inhibition of p38α as a Therapeutic Strategy for Inflammatory Bowel Disease. Gastroenterology, 138 (4). ISSN 0016-5085

Collins, Colm B. and McNamee, Eóin N. and Wermers, Joshua D. and Lebsack, Matthew D.P. and Rivera-Nieves, Jesus (2010) Chemokine decoy receptor D6 in inflammatory bowel disease (IBD) and IBD-associated colon cancer. Gut, 59 (2). ISSN 1468-3288

McNamee, Eóin N. and Griffin, Éadaoin W. and Ryan, Karen M. and Ryan, Katie J. and Heffernan, Sheena and Harkin, Andrew and Connor, Thomas J. (2010) Noradrenaline acting at β-adrenoceptors induces expression of IL-1β and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex. Neuropharmacology, 59. pp. 37-48. ISSN 1873-7064

McNamee, Eóin N. and Ryan, Karen M. and Kilroy, Dana and Connor, Thomas J. (2010) Noradrenaline induces IL-1ra and IL-1 type II receptor expression in primary glial cells and protects against IL-1β-induced neurotoxicity. European Journal of Pharmacology, 626. pp. 219-228. ISSN 0014-2999

McNamee, Eóin N. and Wermers, Joshua D. and Masterson, Joanne C. and Collins, Colm B. and Lebsack, Matthew D.P. and Fillon, Sophie A. and Robinson, Zachary and Grenawalt, Joanna and Lee, James J. and Jedlicka, Paul and Furuta, Glenn T. and Rivera-Nieves, Jesus (2010) A Novel Model of TH2-polarized Chronic Ileitis: The SAMP1 Mouse. Inflammatory Bowel Diseases, 16 (5). pp. 743-752. ISSN 1536-4844