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    Genome analysis of the yeast Diutina catenulata, a member of the Debaryomycetaceae/Metschnikowiaceae (CTG-Ser) clade


    O'Brien, Caoimhe E. and McCarthy, Charley G.P. and Walshe, Annie E. and Shaw, Dennis R. and Sumski, Deirdre A. and Krassowski, Tadeusz and Fitzpatrick, David A. and Butler, Geraldine (2018) Genome analysis of the yeast Diutina catenulata, a member of the Debaryomycetaceae/Metschnikowiaceae (CTG-Ser) clade. PLoS ONE, 13 (6). e0198957. ISSN 1932-6203

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    Abstract

    Diutina catenulata (Candida catenulata) is an ascomycetous yeast that has been isolated from humans, animals and environmental sources. The species is a contaminant of dairy products, and has been linked to superficial and invasive infections in both humans and animals. Previous phylogenetic analyses have assigned the species to the Saccharomycetales, but failed to identify its specific clade. Here, we report the genome sequence of an environmental isolate of D. catenulata. Examination of the tRNA repertoire and coding potential of this species shows that it translates the CUG codon as serine and not leucine. In addition, two phylogenetic analyses using 204 ubiquitous gene family alignments and 3,826 single-copy genes both confirm the placement of the species in the Debaryomycetaceae/Metschnikowiaceae, or CTG-Ser clade. The sequenced isolate contains an MTLα idiomorph. However, unlike most MTL loci in related species, poly (A) polymerase (PAP) is not adjacent to MTLα1.

    Item Type: Article
    Additional Information: Citation: O'Brien CE, McCarthy CGP, Walshe AE, Shaw DR, Sumski DA, Krassowski T, et al. (2018) Genome analysis of the yeast Diutina catenulata, a member of the Debaryomycetaceae/ Metschnikowiaceae (CTG-Ser) clade. PLoS ONE 13 (6): e0198957. https://doi.org/10.1371/journal. pone.0198957. © 2018 O'Brien et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
    Keywords: Genome analysis; yeast; Diutina catenulata; Debaryomycetaceae/Metschnikowiaceae (CTG-Ser) clade;
    Academic Unit: Faculty of Science and Engineering > Biology
    Item ID: 11054
    Identification Number: https://doi.org/10.1371/journal.pone.0198957
    Depositing User: David Fitzpatrick
    Date Deposited: 18 Sep 2019 13:46
    Journal or Publication Title: PLoS ONE
    Publisher: Public Library of Science
    Refereed: Yes
    Funders: University College Dublin, Science Foundation Ireland (SFI), Wellcome Trust
    URI:

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