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    The plant N-end rule pathway: structure and functions

    Graciet, Emmanuelle and Wellmer, Frank (2010) The plant N-end rule pathway: structure and functions. Trends in Plant Science, 15 (8). pp. 447-453. ISSN 1878-4372

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    The N-end rule pathway is a protein degradation pathway that relates the stability of a protein to the nature of its N-terminal amino acid residue. This pathway is part of the ubiquitin–proteasome system in eukaryotes and has been shown to be involved in a multitude of cellular and developmental processes in animals and fungi. However, in plants, its structure and functions have long been enigmatic. In this review, we discuss recent advances in the identification of the enzymatic components that mediate protein degradation through the N-end rule pathway in plants. We further describe the known functions of this pathway in the control of plant growth and development and outline open questions that will likely be the focus of future research.

    Item Type: Article
    Keywords: N-end rule pathway; structure; functions; ubiquitin–proteasome system;
    Academic Unit: Faculty of Science and Engineering > Biology
    Item ID: 11028
    Identification Number:
    Depositing User: Emmanuelle Graciet
    Date Deposited: 09 Sep 2019 14:39
    Journal or Publication Title: Trends in Plant Science
    Publisher: Elsevier
    Refereed: Yes
    Funders: Science Foundation Ireland (SFI)
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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