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    Analysis of hybrids of Candida albicans formed by protoplast fusion

    Law, Carolyn and Kavanagh, Kevin and Whittaker, Peter A. (1994) Analysis of hybrids of Candida albicans formed by protoplast fusion. FEMS Microbiology Letters, 115 (1). pp. 77-82. ISSN 0378-1097

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    A number of hybrids obtained by fusion of protoplasts of complementary auxotrophic strains of Candida albicans were analysed for growth rates, cell volume, DNA content, stability and adherence to human buccal epithelial cells. SDS-PAGE analysis of the cell wall proteins indicated that the hybrid cell walls contained many more of the proteins associated with one parent than the other. The adherence values of the hybrids were closest to the parent with which they shared most cell wall proteins and it is suggested that the hybrids contain the genome of this parent along with one or more of the chromosomes of the other.

    Item Type: Article
    Keywords: Candida; Adherence; Protoplast fusion; Hybrid;
    Academic Unit: Faculty of Science and Engineering > Biology
    Item ID: 11125
    Identification Number:
    Depositing User: Dr. Kevin Kavanagh
    Date Deposited: 04 Oct 2019 13:13
    Journal or Publication Title: FEMS Microbiology Letters
    Publisher: Elsevier B.V.
    Refereed: Yes
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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