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    Minimum Information about a Biosynthetic Gene cluster

    Medema, M.H. and Kottmann, R. and Yilmaz, P. and Cummings, M. and Biggins, J.B. and Blin, K. and de Bruijn, I. and Chooi, Y.H. and Claesen, J. and Coates, R.C. and Cruz-Morales, P. and Duddela, S. and Düsterhus, S. and Edwards, D.J. and Fewer, D.P. and Garg, N. and Geiger, C. and Gomez-Escribano, J.P. and Greule, A. and Hadjithomas, M. and Haines, A.S. and Helfrich, E.J. and Hillwig, M.L. and Ishida, K. and Jones, A.C. and Jones, C.S. and Jungmann, K. and Kegler, C. and Kim, H.U. and Kötter, P. and Krug, D. and Masschelein, J. and Melnik, A.V. and Mantovani, S.M. and Monroe, E.A. and Moore, M. and Moss, N. and Nützmann, H.W. and Pan, G. and Pati, A. and Petras, D. and Reen, F.J. and Rosconi, F. and Rui, Z. and Tian, Z. and Tobias, N.J. and Tsunematsu, Y. and Wiemann, P. and Wyckoff, E. and Yan, X. and Yim, G. and Yu, F. and Xie, Y. and Aigle, B. and Apel, A.K. and Balibar, C.J. and Balskus, E.P. and Barona-Gómez, F. and Bechthold, A. and Bode, H.B. and Borriss, R. and Brady, S.F. and Brakhage, Axel A. and Caffrey, P. and Cheng, Yo and Clardy, J. and Cox, R.J. and De Mot, R. and Donadio, S. and Donia, M.S. and van der Donk, W.A. and Dorrestein, P.C. and Doyle, Sean and Driessen, A.J. and Ehling-Schulz, M. and Entian, K.D. and Fischbach, M.A. and Gerwick, L. and Gerwick, W.H. and Gross, H. and Gust, B. and Hertweck, C. and Höfte, M. and Jensen, S.E. and Ju, J. and Katz, L. and Kaysser, L. and Klassen, J.L. and Keller, N.P. and Kormanec, J. and Kuipers, O.P. and Kuzuyama, T. and Kyrpides, N.C. and Kwon, H.J. and Lautru, S. and Lavigne, R. and Lee, C.Y. and Linquan, B. and Liu, X. and Liu, W. and Luzhetskyy, A. and Mahmud, T. and Mast, Y. and Méndez, C. and Metsä-Ketelä, M. and Micklefield, J. and Mitchell, D.A. and Moore, B.S. and Moreira, L.M. and Muller, R. and Neilan, B.A. and Nett, M. and Nielsen, J. and O'Gara, F. and Oikawa, H. and Osbourn, A. and Osburne, M.S. and Ostash, B. and Payne, S.M. and Pernodet, J.L. and Petricek, M. and Piel, J. and Ploux, O. and Raaijmakers, J.M. and Salas, J.A. and Schmitt, E.K. and Scott, B. and Seipke, R.F. and Shen, B. and Sherman, D.H. and Sivonen, K. and Smanski, M.J. and Sosio, M. and Stegmann, E. and Süssmuth, R.D. and Tahlan, K. and Thomas, C.M. and Tang, Y. and Truman, A.W. and Viaud, M. and Walton, J.D. and Walsh, C.T. and Weber, T. and van Wezel, G.P. and Wilkinson, B. and Willey, J.M. and Wohlleben, W. and Wright, G.D. and Ziemert, N. and Zhang, C. and Zotchev, S.B. and Breitling, R. and Takano, E. and Glöckner, F.O. (2015) Minimum Information about a Biosynthetic Gene cluster. Nature Chemical Biology, 11 (9). pp. 625-631. ISSN 1552-4469

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    A wide variety of enzymatic pathways that produce specialized metabolites in bacteria, fungi and plants are known to be encoded in biosynthetic gene clusters. Information about these clusters, pathways and metabolites is currently dispersed throughout the literature, making it difficult to exploit. To facilitate consistent and systematic deposition and retrieval of data on biosynthetic gene clusters, we propose the Minimum Information about a Biosynthetic Gene cluster (MIBiG) data standard.

    Item Type: Article
    Additional Information: This work is licensed under a Creative Commons Attribution- NonCommercial-ShareAlike 3.0 Unported License. The images or otherthird party material in this article are included in the article ’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit
    Keywords: Biosynthetic Gene cluster; Minimum Information about a Biosynthetic Gene cluster (MIBiG); data standard;
    Academic Unit: Faculty of Science and Engineering > Biology
    Item ID: 11166
    Identification Number:
    Depositing User: Dr. Sean Doyle
    Date Deposited: 08 Oct 2019 16:22
    Journal or Publication Title: Nature Chemical Biology
    Publisher: Nature Research
    Refereed: Yes
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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