Murphy, Sandra and Zweyer, Margit and Mundegar, Rustam R. and Swandulla, Dieter and Ohlendieck, Kay
(2018)
Dataset on the comparative proteomic profiling
of mouse saliva and serum from wild type versus
the dystrophic mdx-4cv mouse model
of dystrophinopathy.
Data in Brief, 21.
pp. 1236-1245.
ISSN 2352-3409
Abstract
The comparative proteomic data presented in this article provide
supporting information to the related research article "Proteomic
identification of elevated saliva kallikrein levels in the mdx-4cv
mouse model of Duchenne muscular dystrophy " (Murphy et al.,
2018). Here we provide additional datasets on the comparative
proteomic analysis of saliva and serum proteins and the mass
spectrometric identification of kallikrein isoform Klk-1 in wild type
versus mdx-4cv saliva specimens. The data article presents the
systematic identification of the assessable saliva proteome and the
differential presence of proteins in saliva versus serum samples.
Representative mass spectrometric scans of unique peptides that
were employed to identify the kallikrein isoform Klk-1 in wild type
versus mdx-4cv saliva specimens are provided. The dataset contains typical saliva-associated marker proteins, including alphaamylase and albumin, as well as distinct isoforms of cystatin,
serpin, kallikrein, cathepsin, glutathione transferase, carbonic
anhydrase, mucin, pyruvate kinase, and aldolase.
| Item Type: |
Article
|
| Keywords: |
Dataset; comparative; proteomic; profiling;
mouse saliva; serum; wild type; versus;
dystrophic; mdx-4cv; mouse model;
dystrophinopathy; |
| Academic Unit: |
Faculty of Science and Engineering > Biology |
| Item ID: |
13142 |
| Identification Number: |
https://doi.org/10.1016/j.dib.2018.10.082 |
| Depositing User: |
Prof. Kay Ohlendieck
|
| Date Deposited: |
22 Jul 2020 15:45 |
| Journal or Publication Title: |
Data in Brief |
| Publisher: |
Elsevier |
| Refereed: |
Yes |
| Funders: |
Hume scholarship (Maynooth University), Muscular Dystrophy Ireland, Health Research Board (HRB), Science Foundation Ireland (SFI) |
| URI: |
|
| Use Licence: |
This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available
here |
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