Walsh, Fiona and Bracher, S. and Turner, P. and Amyes, Sebastian G.B. (2007) Preferential Selection of IMP and VIM Metallo-β-Lactamases by Imipenem in Pseudomonas aeruginosa. Experimental Chemotherapy, 53. pp. 407-409. ISSN 0536–0407

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Abstract

Mixed populations of Pseudomonas aeruginosa, comprising a carbapenem-susceptible and a carbapenem-resistant strain, containing either the IMP or VIM -lactamases, were exposed to imipenem. They developed resistance to both imipenem and meropenem. When the same mixed populations were exposed to meropenem, only the mixture containing the VIM -lactamases became resistant to both carbapenems.

Item Type:	Article
Keywords:	Competition studies Carbapenems; Metallo-β-lactamase;
Academic Unit:	Faculty of Science and Engineering > Biology
Item ID:	13553
Identification Number:	https://doi.org/10.1159/000109815
Depositing User:	Fiona Walsh
Date Deposited:	09 Nov 2020 16:54
Journal or Publication Title:	Experimental Chemotherapy
Publisher:	Karger
Refereed:	Yes
URI:	Publisher
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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