Schneider, Marc and Retz, Wolfgang and Coogan, Andrew and Thome, Johannes and Rösler, Michael (2006) Anatomical and functional brain imaging in adult attention-deficit/hyperactivity disorder (ADHD)—A neurological view. European Archives of Psychiatry and Clinical Neuroscience, 256 (S1). i32-i41. ISSN 0940-1334

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Abstract

In this review, we discuss current structural and functional imaging data on ADHD in a neurological and neuroanatomical framework. At present, the literature on adult ADHD is somewhat sparse, and so results from imaging have to therefore be considered mainly from the childhood or adolescence perspective. Most work has considered the impairment of executive functions (motor execution, inhibition, working memory), and as such a number of attention networks and their anatomical correlates are discussed in this review (e. g. the cerebello-(thalamo-)-striato-cortical network seems to play a pivotal role in ADHD pathology from childhood to adulthood). The core findings in ADHD imaging are alterations in the architecture and function of prefrontal cortex and cerebellum. The dorsal part of anterior cingulated cortex (dACC) is an important region for decision making, and executive control is impaired in adult ADHD. Finally, dysfunction of basal ganglia is a consistent finding in childhood and adulthood ADHD, reflecting dysregulation of fronto-striatal circuitry. The cerebellum, and its role in affect and cognition, is also persistently implicated in the pathology of ADHD.

Item Type:	Article
Keywords:	attention-deficit; hyperactivity disorder; ADHD; magnetic resonance imaging; MRI; review;
Academic Unit:	Assisting Living & Learning,ALL institute Faculty of Science and Engineering > Psychology Faculty of Science and Engineering > Research Institutes > Human Health Institute
Item ID:	16465
Identification Number:	https://doi.org/10.1007/s00406-006-1005-3
Depositing User:	Dr. Andrew Coogan
Date Deposited:	30 Aug 2022 15:27
Journal or Publication Title:	European Archives of Psychiatry and Clinical Neuroscience
Publisher:	Springer
Refereed:	Yes
URI:	Publisher
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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