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    Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021


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    Funk, Tjede, Pharris, Anastasia, Spiteri, Gianfranco, Bundle, Nick, Melidou, Angeliki, Carr, Michael, Gonzalez, Gabriel, Garcia-Leon, Alejandro, Crispie, Fiona, O’Connor, Lois, Murphy, Niamh, Mossong, Joël, Vergison, Anne, Wienecke-Baldacchino, Anke K., Abdelrahman, Tamir, Riccardo, Flavia, Stefanelli, Paola, Di Martino, Angela, Bella, Antonino, Lo Presti, Alessandra, Casaca, Pedro, Moreno, Joana, Borges, Vítor, Isidro, Joana, Ferreira, Rita, Gomes, João Paulo, Dotsenko, Liidia, Suija, Heleene, Epstein, Jevgenia, Sadikova, Olga, Sepp, Hanna, Ikonen, Niina, Savolainen-Kopra, Carita, Blomqvist, Soile, Möttönen, Teemu, Helve, Otto, Gomes-Dias, Joana, Adlhoch, Cornelia and Walsh, Fiona (2021) Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021. Eurosurveillance, 26 (16). ISSN 1560-7917

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    Abstract

    We compared 19,207 cases of SARS-CoV-2 variant B.1.1.7/S gene target failure (SGTF), 436 B.1.351 and 352 P.1 to non-variant cases reported by seven European countries. COVID-19 cases with these variants had significantly higher adjusted odds ratios for hospitalisation (B.1.1.7/SGTF: 1.7, 95% confidence interval (CI): 1.0–2.9; B.1.351: 3.6, 95% CI: 2.1–6.2; P.1: 2.6, 95% CI: 1.4–4.8) and B.1.1.7/SGTF and P.1 cases also for intensive care admission (B.1.1.7/SGTF: 2.3, 95% CI: 1.4–3.5; P.1: 2.2, 95% CI: 1.7–2.8). Here, we analyse coronavirus disease (COVID-19) cases infected with any of the three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOC): B.1.1.7/S gene target failure (SGTF), B.1.351 or P.1. We compare them with cases reported as infected with non-VOC virus with a focus on disease severity.
    Item Type: Article
    Additional Information: Cite as: Funk Tjede, Pharris Anastasia, Spiteri Gianfranco, Bundle Nick, Melidou Angeliki, Carr Michael, Gonzalez Gabriel, Garcia-Leon Alejandro, Crispie Fiona, O’Connor Lois, Murphy Niamh, Mossong Joël, Vergison Anne, Wienecke-Baldacchino Anke K., Abdelrahman Tamir, Riccardo Flavia, Stefanelli Paola, Di Martino Angela, Bella Antonino, Lo Presti Alessandra, Casaca Pedro, Moreno Joana, Borges Vítor, Isidro Joana, Ferreira Rita, Gomes João Paulo, Dotsenko Liidia, Suija Heleene, Epstein Jevgenia, Sadikova Olga, Sepp Hanna, Ikonen Niina, Savolainen-Kopra Carita, Blomqvist Soile, Möttönen Teemu, Helve Otto, Gomes-Dias Joana, Adlhoch Cornelia, on behalf of COVID study groups. Characteristics of SARS-CoV-2 variants of concern B.1.1.7, B.1.351 or P.1: data from seven EU/EEA countries, weeks 38/2020 to 10/2021. Euro Surveill. 2021;26(16):pii=2100348. https://doi.org/10.2807/1560-7917.ES.2021.26.16.2100348
    Keywords: SARS-CoV-2; Covid-19; antibodies;
    Academic Unit: Faculty of Science and Engineering > Biology
    Faculty of Science and Engineering > Research Institutes > Human Health Institute
    Item ID: 17350
    Identification Number: 10.2807/1560-7917.ES.2021.26.16.2100348
    Depositing User: Fiona Walsh
    Date Deposited: 22 Jun 2023 13:56
    Journal or Publication Title: Eurosurveillance
    Publisher: Centre Europeen pour la Surveillance Epidemiologique du SIDA (European Centre for the Epidemiological Monitoring of AIDS)
    Refereed: Yes
    URI: https://mural.maynoothuniversity.ie/id/eprint/17350
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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