Dunbar, Hazel and Hawthorne, Ian James and English, Karen
(2024)
MAC attack: MSCs and macrophages join forces against chronic lung infection.
Thorax.
ISSN 0040-6376
Abstract
Mesenchymal stromal cells (MSCs)
possess several characteristics that make
them attractive as a potential adjunct
therapy for acute and chronic infectious
diseases. MSCs are well known for their
impressive immunomodulatory, prorepair effects and clinical safety
profile, however, the efficacy of MSCs
in controlling bacterial infections, at least
directly, remains unclear.
Mycobacterium avium complex pulmonary disease (MAC-PD) is a chronic condition driven by multi-drug resistant bacteria
for which there are no robust efficacious
treatment strategies.
| Item Type: |
Article
|
| Keywords: |
MAC attack; MSCs; macrophages; chronic lung infection; |
| Academic Unit: |
Faculty of Science and Engineering > Biology |
| Item ID: |
18355 |
| Identification Number: |
https://doi.org/10.1136/thorax-2024-221637 |
| Depositing User: |
Karen English
|
| Date Deposited: |
08 Apr 2024 10:59 |
| Journal or Publication Title: |
Thorax |
| Publisher: |
BMJ Publishing Group |
| Refereed: |
Yes |
| URI: |
|
| Use Licence: |
This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available
here |
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