Dunbar, Hazel and Hawthorne, Ian James and English, Karen (2024) MAC attack: MSCs and macrophages join forces against chronic lung infection. Thorax. ISSN 0040-6376

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Abstract

Mesenchymal stromal cells (MSCs) possess several characteristics that make them attractive as a potential adjunct therapy for acute and chronic infectious diseases. MSCs are well known for their impressive immunomodulatory, prorepair effects and clinical safety profile, however, the efficacy of MSCs in controlling bacterial infections, at least directly, remains unclear. Mycobacterium avium complex pulmonary disease (MAC-PD) is a chronic condition driven by multi-drug resistant bacteria for which there are no robust efficacious treatment strategies.

Item Type:	Article
Keywords:	MAC attack; MSCs; macrophages; chronic lung infection;
Academic Unit:	Faculty of Science and Engineering > Biology
Item ID:	18355
Identification Number:	https://doi.org/10.1136/thorax-2024-221637
Depositing User:	Karen English
Date Deposited:	08 Apr 2024 10:59
Journal or Publication Title:	Thorax
Publisher:	BMJ Publishing Group
Refereed:	Yes
URI:	Publisher
Use Licence:	This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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