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    Investigating the Relationship between Topology and Evolution in a Dynamic Nematode Odor Genetic Network

    Fitzpatrick, David A. and O'Halloran, Damien M. (2012) Investigating the Relationship between Topology and Evolution in a Dynamic Nematode Odor Genetic Network. International Journal of Evolutionary Biology, 2012 (548081). ISSN 2090-052X

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    The relationship between biological network architectures and evolution is unclear. Within the phylum nematoda olfaction represents a critical survival tool. For nematodes, olfaction contributes to multiple processes including the finding of food, hosts, and reproductive partners, making developmental decisions, and evading predators. Here we examine a dynamic nematode odor genetic network to investigate how divergence, diversity, and contribution are shaped by network topology. Our findings describe connectivity frameworks and characteristics that correlate with molecular evolution and contribution across the olfactory network. Our data helps guide the development of a robust evolutionary description of the nematode odor network that may eventually aid in the prediction of interactive and functional qualities of novel nodes.

    Item Type: Article
    Keywords: Topology; Evolution; Dynamic Nematode Odor Genetic Network;
    Academic Unit: Faculty of Science and Engineering > Biology
    Item ID: 3974
    Depositing User: David Fitzpatrick
    Date Deposited: 12 Nov 2012 15:01
    Journal or Publication Title: International Journal of Evolutionary Biology
    Publisher: SAGE-Hindawi Access to Research
    Refereed: Yes
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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