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    Biomarker responses to weaning stress in beef calves

    O'Loughlin, Aran and McGee, Mark and Doyle, Sean and Earley, Bernadette (2014) Biomarker responses to weaning stress in beef calves. Research in Veterinary Science, 97 (2). pp. 457-463. ISSN 0034-5288

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    The study objective was to investigate the physiological effects of weaning on beef calves and identify a panel of blood-based welfare biomarkers. On the day (d) of weaning (d 0), 16 spring-born, singlesuckled, beef bull calves that previously grazed with their dams at pasture, were assigned to one of two treatments: (1) control (n = 8), calves were loose-housed with their dam, (2) weaned (n = 8), calves were abruptly separated from their dam and loose-housed. Jugular blood was collected on d −4, 0, 1, 2, 3, 7, and 14 relative to weaning (d 0) and assayed for inflammatory and steroid variables. Total leukocyte counts were measured in whole blood. It is concluded that neutrophil number is a robust biomarker of stress and that plasma CXCL8 is a sensitive indicator of stress in weaned and control calves. In future studies, these two biomarkers should be central to the characterisation of stress responses.

    Item Type: Article
    Keywords: Cattle; Weaning; Stress; Biomarkers; Haematology; Cortisol; CXCL8;
    Academic Unit: Faculty of Science and Engineering > Biology
    Item ID: 7388
    Identification Number:
    Depositing User: Dr. Sean Doyle
    Date Deposited: 26 Aug 2016 14:48
    Journal or Publication Title: Research in Veterinary Science
    Publisher: Elsevier
    Refereed: Yes
    Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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