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Kavanagh, Kevin and Reeves, Emer P. (2007) Insect and Mammalian Innate Immune Responses Are Much Alike. Microbe, 2 (12). pp. 596-599. ISSN 1558-7460
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Abstract
The innate immune systems of mammals and
insects have several features in common. Both insect hemocytes and mammalian neutrophils
engulf and kill pathogens, and both types
of cell produce superoxide, using extraordinarily
similar p47 and p67 proteins. Larvae of the greater wax moth Galleria mellonella
provide a model system for evaluating
familiar bacterial and fungal pathogens as well
as for testing candidate antimicrobials. Insect immune systems function cooperatively
and exhibit both humoral and cellular
components.
| Item Type: | Article |
|---|---|
| Keywords: | Insect; Mammal; Innate Immune Responses; |
| Academic Unit: | Faculty of Science and Engineering > Biology |
| Item ID: | 11133 |
| Depositing User: | Dr. Kevin Kavanagh |
| Date Deposited: | 04 Oct 2019 16:23 |
| Journal or Publication Title: | Microbe |
| Publisher: | American Society for Microbiology |
| Refereed: | Yes |
| Funders: | Higher Education Authority (HEA) |
| URI: | https://mural.maynoothuniversity.ie/id/eprint/11133 |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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