Share and Export
Share and Export
Amyes, Sebastian G.B., Walsh, Fiona and Bradley, John S. (2007) Best in class: a good principle for antibiotic usage to limit resistance development? Journal of Antimicrobial Chemotherapy, 59. pp. 825-826. ISSN 0305-7453
Preview
FW_best in class.pdf
Download (85kB) | Preview
Abstract
The causes of antibiotic resistance are often complex and it is difficult to identify strategies to prevent or delay its emergence. One strategy has been to use less active members of a drug class, so that when resistance develops the more active members will still prevail. This stratagem may often fail because this resistance may form the basis of resistance to the whole class. Often, less active drugs are the first to be discovered and more active versions follow, so we have had no choice; however, increasingly less active drugs are available to deal with specific infections and this may have a detrimental effect on the class as a whole.
| Item Type: | Article |
|---|---|
| Keywords: | antimicrobial management; therapy; carbapenems; |
| Academic Unit: | Faculty of Science and Engineering > Biology |
| Item ID: | 12672 |
| Identification Number: | 10.1093/jac/dkm059 |
| Depositing User: | Fiona Walsh |
| Date Deposited: | 31 Mar 2020 12:52 |
| Journal or Publication Title: | Journal of Antimicrobial Chemotherapy |
| Publisher: | Oxford University Press |
| Refereed: | Yes |
| Related URLs: | |
| URI: | https://mural.maynoothuniversity.ie/id/eprint/12672 |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
Repository Staff Only (login required)
- Item control page
Downloads
Downloads per month over past year
