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O'Connor, David and Jones, Gary (2006) Chaperoning prions: the story unfolds. Biotech International (18). pp. 6-10.
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Abstract
Prions are infectious proteins that
are responsible for a number of
mammalian degenerative diseases.
The discovery of prions in
yeast has allowed detailed genetic
analysis to be carried out to
identify cellular factors involved
in prion propagation. It is now
clear that a complex relationship
exists between molecular chaperones
and prion propagation.
Prions may actually have evolved
to exploit the cell's chaperone
machinery to ensure their own
propagation.
| Item Type: | Article |
|---|---|
| Keywords: | prions; prion propagation; chaperones; yeast; |
| Academic Unit: | Faculty of Science and Engineering > Research Institutes > Hamilton Institute |
| Item ID: | 6020 |
| Identification Number: | http://www.biotech-online.com |
| Depositing User: | Dr. Gary Jones |
| Date Deposited: | 10 Apr 2015 16:12 |
| Journal or Publication Title: | Biotech International |
| Publisher: | PanGlobal Media |
| Refereed: | No |
| URI: | https://mural.maynoothuniversity.ie/id/eprint/6020 |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
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