Share and Export
Share and Export
McGinley, John, McCann, Malachy, Ni, Kaijie, Tallon, Theresa M., Kavanagh, Kevin, Devereux, Michael, Ma, Xiaomei and McKee, Vickie (2013) Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities. Polyhedron, 55. pp. 169-178. ISSN 0277-5387
Preview
KK-Imidazole.pdf
Download (309kB) | Preview
Abstract
1-(3-Aminopropyl)imidazole (Apim) reacts with salicylaldeh yde and a selection of imidazole aldehydes
and the resulting Schiff base ligands readily coordinate to Zn(II), Cu(II) and Ag(I) centres. X-ray crystal
structures were obtained for two of the free ligands and also the Ag(I) complex of the Apim-salicylaldehyde
ligand. Encouragingly, all of free ligands and most of their metal complexes are relatively non-toxic,
in vivo , towards Galleria mellonella . Although the free ligands and the Cu(II) and Zn(II) complexes are inactive,
in vitro , against a selection of microbial pathogens, most of the Ag(I) complexes exhibit moderate
anti-bacterial activity and good anti-fungal activity.
| Item Type: | Article |
|---|---|
| Additional Information: | The definitive published version of this article is available at DOI: 10.1016/j.poly.2013.03.023 |
| Keywords: | Imidazoles; Schiff bases; Metal complexes; X-ray; Antimicrobial; Galleria mellonella; |
| Academic Unit: | Faculty of Science and Engineering > Biology |
| Item ID: | 6891 |
| Identification Number: | 10.1016/j.poly.2013.03.023 |
| Depositing User: | Dr. Kevin Kavanagh |
| Date Deposited: | 20 Jan 2016 13:21 |
| Journal or Publication Title: | Polyhedron |
| Publisher: | Elsevier |
| Refereed: | Yes |
| Related URLs: | |
| URI: | https://mural.maynoothuniversity.ie/id/eprint/6891 |
| Use Licence: | This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here |
Repository Staff Only (login required)
- Item control page
Downloads
Downloads per month over past year
