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Downes, Shane G. and Owens, Rebecca A. and Walshe, Kieran and Fitzpatrick, David A. and Dorey, Amber and Jones, Gary W. and Doyle, Sean (2023) Gliotoxin-mediated bacterial growth inhibition is caused by specific metal ion depletion. Scientific Reports, 13 (1). ISSN 2045-2322
Doyle, Sean and Cuskelly, Daragh D. and Conlon, Niall and Fitzpatrick, David A. and Gilmartin, Ciara B. and Dix, Sophia H. and Jones, Gary W. (2022) A Single Aspergillus fumigatus Gene Enables Ergothioneine Biosynthesis and Secretion by Saccharomyces cerevisiae. International Journal of Molecular Sciences, 23 (18). p. 10832. ISSN 1422-0067
Traynor, Aimee M. and Owens, Rebecca A. and Coughlin, Claudia M. and Holton, Maeve C. and Jones, Gary W. and Calera, José A. and Doyle, Sean (2021) At the metal–metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin. Microbiology, 167 (11). ISSN 1350-0872
Traynor, Aimee M. and Owens, Rebecca A. and Coughlin, Claudia M. and Holton, Maeve C. and Jones, Gary W. and Calera, José A. and Doyle, Sean (2021) At the metal–metabolite interface in Aspergillus fumigatus: towards untangling the intersecting roles of zinc and gliotoxin. Microbiology, 167 (11). ISSN 1350-0872
Xu, Linan and Zhang, Hong and Cuskelly, Daragh D. and Doyle, Sean and Perrett, Sarah and Jones, Gary W. (2021) Mutational analysis of the Hsp70 substrate‐binding domain: Correlating molecular‐level changes with in vivo function. Molecular Microbiology, 115 (6). pp. 1262-1276. ISSN 0950-382X
Xu, Linan and Nitika and Hasin, Naushaba and Cuskelly, Daragh and Wolfgeher, Donald and Doyle, Sean and Moynagh, Paul N. and Perrett, Sarah and Jones, Gary W. and Truman, Andrew W. (2019) Rapid deacetylation of yeast Hsp70 mediates the cellular response to heat stress. Scientific Reports, 9 (16260). ISSN 2045-2322
Doyle, Sean and Jones, Gary W. and Dolan, Stephen K. (2018) Dysregulated gliotoxin biosynthesis attenuates the production of unrelated biosynthetic gene cluster-encoded metabolites in Aspergillus fumigatus. Fungal Biology, 122. pp. 214-221. ISSN 1878-6146
Saleh, Aliabbas A. and Jones, Gary W. and Tinley, Frances C. and Delaney, Stephen F. and Alabaddi, Sahar H. and Fenlon, Keith and Doyle, Sean and Owens, Rebecca A. (2018) Systems impact of zinc chelation by the epipolythiodioxopiperazine dithiol gliotoxin in Aspergillus fumigatus: a new direction in natural product functionality. Metallomics, 10. pp. 854-866. ISSN 1756-591X
Manfiolli, Adriana Oliveira and Alves de Castro, Patricia and Fernanda dos Reis, Thaila and Dolan, Stephen K. and Doyle, John and Jones, Gary W. and Riano-Pachon, Diego Mauricio and Ulas, Mevlut and Noble, Luke M. and Mattern, Derek J. and Brakhage, Axel A. and Valiante, Vito and Silva-Rocha, Rafael and Bayram, Ozgur and Goldman, Gustavo H. (2017) Aspergillus fumigatus protein phosphatase PpzA is involved in iron assimilation, secondary metabolite production, and virulence. Cellular Microbiology, 19 (e12770). ISSN 1462-5822
Dolan, Stephen K. and Bock, Tobias and Hering, Vanessa and Owens, Rebecca A. and Jones, Gary W. and Blankenfeldt, Wulf and Doyle, Sean (2017) Structural, mechanistic and functional insight into gliotoxin bis-thiomethylation in Aspergillus fumigatus. Open Biology, 7 (2). ISSN 2046-2441
Alves de Castro, Patricia and dos Reis, Thaila Fernanda and Dolan, Stephen K. and Manfiolli, Adriana Oliveira and Brown, Neil Andrew and Jones, Gary W. and Doyle, Sean and Riaño‐Pachón, Diego M. and Squina, Fabio M. and Caldana, Camila and Singh, Ashutosh and Del Poeta, Maurizio and Hagiwara, Daisuke and Silva-Rocha, Rafael and Goldman, Gustavo H. (2016) The Aspergillus fumigatus SchASCH9 kinase modulates SakAHOG1 MAP kinase activity and it is essential for virulence. Molecular Microbiology, 102 (4). pp. 642-671. ISSN 1365-2958
Sheridan, Kevin J. and Lechner, Beatrix Elizabeth and O'Keeffe, Grainne and Keller, Markus A. and Werner, Ernst R. and Lindner, Herbert and Jones, Gary W. and Haas, Hubertus and Doyle, Sean (2016) Ergothioneine Biosynthesis and Functionality in the Opportunistic Fungal Pathogen, Aspergillus fumigatus. Scientific Reports, 6 (35306). ISSN 2045-2322
Manzanares-Miralles, Lara and Bayram, Ozgur and Sarikaya-Bayram, Ozlem and Smith, Elizabeth B. and Dolan, Stephen K. and Jones, Gary W. and Doyle, Sean (2016) Quantitative proteomics reveals the mechanism and consequence of gliotoxin-mediated dysregulation of the methionine cycle in Aspergillus niger. Journal of Proteomics, 131. pp. 149-162. ISSN 1874-3919
Smith, Elizabeth B. and Dolan, Stephen K. and Fitzpatrick, David A. and Doyle, Sean and Jones, Gary W. (2016) Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity. Microbial Cell, 3 (3). pp. 120-125. ISSN 2311-2638
Ade, P.A.R. and Aghanim, N. and Armitage-Caplan, C. and Arnaud, Martha B. and Ashdown, M. and Atrio-Barandela, F. and Aumont, J. and Aussel, H. and Baccigalupi, C. and Banday, A.J. and Barreiro, R.B. and Barrena, R. and Bartelmann, M. and Bartlett, J.G. and Battaner, E. and Benabed, K. and Benoit, A. and Benoit-Lévy, A. and Bernard, J.-P. and Bersanelli, M. and Bielewicz, P. and Bikmaev, I. and Bobin, J. and Bock, J.J. and Böhringer, H. and Bonaldi, A. and Bond, J.R. and Borrill, J. and Bouchet, F.R. and Bridges, M. and Bucher, M. and Burenin, R. and Burigana, C. and Butler, R.C. and Cardoso, J.-F. and Carvalho, P. and Catalano, A. and Challinor, A. and Chamballu, A. and Chary, R.-R. and Chen, X. and Chiang, H.C. and Chiang, L.-Y. and Chon, G. and Christensen, P.R. and Churazov, E. and Church, S. and Clements, D.L. and Colombi, S. and Colombo, L.P.L. and Comis, B. and Couchot, F. and Coulais, A. and Crill, B.P. and Curto, A. and Cuttaia, F. and Da Silva, A. and Dahle, H. and Danese, L. and Davies, R.D. and Davis, R.J. and De Bernardis, P. and de Rosa, A. and de Zotti, G. and Delabrouille, J. and Delouis, J.-M. and Démoclès, J. and Desert, F.-X. and Dickinson, C. and Diego, J.M. and Dolag, K. and Dole, H. and Donzelli, S. and Dore, O. and Douspis, M. and Dupac, X. and Efstathiou, G. and Enßlin, T.A. and Eriksen, H.K. and Feroz, F. and Ferragamo, A. and Finelli, F. and Flores-Cacho, I. and Forni, O. and Frailis, M. and Franceschi, E. and Fromenteau, S. and Galeotta, S. and Ganga, K. and Genova-Santos, R.T. and Giard, M. and Giardino, G. and Gilfanov, M. and Giraud-Héraud, Y. and Gonzalez-Nuevo, J. and Gorski, K.M. and Grainge, K.J.B. and Gratton, S. and Gregorio, A. and Groeneboom, N.E. and Gruppuso, A. and Hansen, F.K. and Hanson, D. and Harrison, D. and Hempel, A. and Henrot-Versille, S. and Hernandez-Monteagudo, C. and Herranz, D. and Hildebrandt, S.R. and Hivon, E. and Hobson, M. and Holmes, W.A. and Hornstrup, A. and Hovest, W. and Huffenberger, K.M. and Hurier, G. and Hurley-Walker, N. and Jaffe, A.H. and Jaffe, T.R. and Jones, Gary W. and Juvela, M. and Keihanen, E. and Keskitalo, R. and Khamitov, I. and Kisner, T.S. and Kneissl, R. and Knoche, J. and Knox, L. and Kunz, M. and Kurki-Suonio, H. and Lagache, G. and Lahteenmaki, A. and Lamarre, J.-M. and Lasenby, A. and Laureijs, R.J. and Lawrence, C.R. and Leahy, J.P. and Leonardi, R. and Leon-Tavares, J. and Lesgourgues, J. and Li, C. and Liddle, A. and Liguori, M. and Lilje, P.B. and Linden-Vornle, M. and Lopez-Caniego, M. and Lubin, P.M. and Macias-Perez, J.F. and MacTavish, C.J. and Maffei, B. and Maino, D. and Mandolesi, N. and Maris, M. and Marshall, D.J. and Martin, P.G. and Martinez-Gonzalez, E. and Masi, S. and Massardi, M. and Matarrese, S. and Matthai, F. and Mazzotta, P. and Mei, S. and Meinhold, P.R. and Melchiorri, A. and Melin, J.-B. and Mendes, L. and Mennella, A. and Migliaccio, M. and Mikkelsen, K. and Mitra, S. and Miville-Deschenes, M.-A. and Moneti, A. and Montier, L. and Morgante, G. and Mortlock, D. and Munshi, D. and Murphy, J.Anthony and Naselsky, P. and Nastasi, A. and Nati, F. and Natoli, P. and Nesvadba, N.P.H. and Netterfield, C.B. and Norgaard-Nielsen, H.U. and Noviello, F. and Novikov, D. and Novikov, I. and O'Dwyer, I.J. and Olamaie, M. and Osborne, S. and Oxborrow, C.A. and Paci, F. and Pagano, L. and Pajot, F. and Paoletti, D. and Pasian, F. and Patanchon, G. and Pearson, T.J. and Perdereau, O. and Perotto, L. and Perrott, Y.C. and Perrotta, F. and Piacentini, F. and Piat, M. and Pierpaoli, E. and Pietrobon, D. and Plaszczynski, S. and Pointecouteau, E. and Polenta, G. and Ponthieu, N. and Popa, L. and Poutanen, T. and Pratt, G.W. and Prezeau, G. and Prunet, S. and Puget, J.-L. and Rachen, J.P. and Reach, W.T. and Rebolo, R. and Reinecke, M. and Remazeilles, M. and Renault, C. and Ricciardi, S. and Riller, T. and Ristorcelli, I. and Rocha, G. and Rosset, C. and Roudier, G. and Rowan-Robinson, M. and Rubino-Martin, J.A. and Rumsey, C. and Rusholme, B. and Sandri, M. and Santos, D. and Saunders, R.D.E. and Savini, G. and Schammel, M.P. and Scott, D. and Seiffert, M.D. and Shellard, E.P.S. and Shimwell, T.W. and Spencer, L. and Starck, J.-L. and Stolyarov, V. and Stompor, R. and Streblyanska, A. and Sudiwala, R. and Sunyaev, R. and Sureau, F. and Sutton, D. and Suur-Uski, A.-S. and Sygnet, J.-F. and Tauber, J.A. and Tavagnacco, D. and Terenzi, L. and Toffolatti, L. and Tomasi, M. and Tramonte, D. and Tristram, M. and Tucci, M. and Tuovinen, J. and Turler, M. and Umana, G. and Valenziano, L. and Valiviita, J. and Van Tent, B. and Vibert, L. and Vielva, P. and Villa, F. and Vittorio, N. and Wade, L.A. and Wandelt, B.D. and White, M. and White, S.D.M. and Yvon, D. and Zacchei, A. and Zonca, A. (2015) Planck 2013 results. XXXII. The updated Planck catalogue of Sunyaev-Zeldovich sources. Astronomy & Astrophysics, 581 (A141). ISSN 0004-6361
Dolan, Stephen K. and O'Keefe, Grainne and Jones, Gary W. and Doyle, Sean (2015) Resistance is not futile: gliotoxin biosynthesis, functionality and utility. Trends in Microbiology, 23 (7). pp. 419-428. ISSN 0966-842X
Winkelstroter, Lizziane K. and Dolan, Stephen K. and Fernanda dos Reis, Thaila and Pedro Bom, Vinicius Leite and Alves de Castro, Patricia and Hagiwara, Daisuke and Alowni, Raneem and Jones, Gary W. and Doyle, Sean and Brown, Neil Andrew and Goldman, Gustavo H. (2015) Systematic Global Analysis of Genes Encoding Protein Phosphatases in Aspergillus fumigatus. G3 : Genes, Genomes, Genetics, 5. pp. 1525-1539. ISSN 2160-1836
Hasin, Naushaba and Cusack, Sarah and Ali, Shahin S. and Fitzpatrick, David A. and Jones, Gary W. (2014) Global transcript and phenotypic analysis of yeast cells expressing Ssa1, Ssa2, Ssa3 or Ssa4 as sole source of cytosolic Hsp70-Ssa chaperone activity. BMC Genomics, 15 (194). pp. 1-12. ISSN 1471-2164
He, Jianwei and Wang, Yu and Chang, Alan K. and Xu, Linan and Wang, Na and Chong, Xiaoying and Li, Hui and Zhang, Bing and Jones, Gary W. and Song, Youtao (2014) Myricetin Prevents Fibrillogenesis of Hen Egg White Lysozyme. Journal of Agricultural and Food Chemistry, 62. pp. 9442-9449. ISSN 0021-8561
Keane, Orla M. and Toft, Christina and Carretero-Paulet, Lorenzo and Jones, Gary W. and Fares, Mario A. (2014) Preservation of Genetic and Regulatory Robustness in Ancient Gene Duplicates of Saccharomyces cerevisiae. Genome Research, 14. pp. 1-29. ISSN 1088-9051
Owens, Rebecca A. and Hammel, Stephen and Sheridan, Kevin J. and Jones, Gary W. and Doyle, Sean (2014) A Proteomic Approach to Investigating Gene Cluster Expression and Secondary Metabolite Functionality in Aspergillus fumigatus. PLoS ONE, 9 (9). e106942. ISSN 1932-6203
O’Keeffe, Grainne and Hammel, Stephen and Owens, Rebecca A. and Keane, Thomas M. and Fitzpatrick, David A. and Jones, Gary W. and Doyle, Sean (2014) RNA-seq reveals the pan-transcriptomic impact of attenuating the gliotoxin self-protection mechanism in Aspergillus fumigatus. BMC Genomics, 15 (894). pp. 1-26. ISSN 1471-2164
Dolan, Stephen K. and Owens, Rebecca A. and O'Keefe, Grainne and Hammel, Stephen and Fitzpatrick, David A. and Jones, Gary W. and Doyle, Sean (2014) Regulation of Nonribosomal Peptide Synthesis: bis-Thiomethylation Attenuates Gliotoxin Biosynthesis in Aspergillus fumigatus. Chemistry and Biology, 21 (8). pp. 999-2012. ISSN 1074-5521
Jones, Gary W. and Doyle, Sean and Fitzpatrick, David A. (2014) The evolutionary history of the genes involved in the biosynthesis of the antioxidant ergothioneine. Gene, 549 (1). pp. 161-170. ISSN 0378-1119
Moran, Ciara and Kinsella, Gemma K. and Zhang, Zai-Rong and Perrett, Sarah and Jones, Gary W. (2013) Mutational Analysis of Sse1 (Hsp110) Suggests an Integral Role for this Chaperone in Yeast Prion Propagation In Vivo. G3. ISSN 2160-1836
Fares, Mario A. and Keane, Orla M. and Toft, Christina and Carretero-Paulet, Lorenzo and Jones, Gary W. (2013) The Roles of Whole-Genome and Small-Scale Duplications in the Functional Specialization of Saccharomyces cerevisiae Genes. PLos Genetics, 9 (1). e1003176. ISSN 1553-7390
Xu, Li-Qiong and Wu, Si and Buell, Alexander K. and Cohen, Samuel I.A. and Chen, Li-Jun and Hu, Wan-Hui and Cusack, Sarah and Itzhaki, Laura S. and Zhang, Hong and Knowles, Tuomas P.J. and Dobson, Christopher M. and Welland, Mark E. and Jones, Gary W. and Perrett, Sarah (2013) Influence of specific HSP70 domains on fibril formation of the yeast prion protein Ure2. Philosophical Transactions of the Royal Society B, 368 (1617). p. 20110410. ISSN 0962-8436
Xu, Linan and Hasin, Naushaba and Shen, Manli and He, Jianwei and Xue, Youlin and Zhou, Xiaohong and Perrett, Sarah and Song, Youtao and Jones, Gary W. (2013) Using Steered Molecular Dynamics to Predict and Assess Hsp70 Substrate-Binding Domain Mutants that Alter Prion Propagation. PLoS Computational Biology, 9 (1). ISSN 1553-734X
Truman, Andrew W. and Kristjansdottir, Kolbrun and Wolfgeher, Donald and Hasin, Naushaba and Polier, Sigrun and Zhang, Hong and Perrett, Sarah and Prodromou, Chrisostomos and Jones, Gary W. and Kron, Stephen J. (2012) CDK-Dependent Hsp70 Phosphorylation Controls G1 Cyclin Abundance and Cell-Cycle Progression. Cell, 151 (6). pp. 1308-1318. ISSN 0092-8674
Carberry, Stephen and Molloy, Emer and Hammel, Stephen and O'Keefe, Grainne and Jones, Gary W. and Kavanagh, Kevin and Doyle, Sean (2012) Gliotoxin effects on fungal growth: Mechanisms and exploitation. Fungal Genetics and Biology, 49 (4). pp. 302-312. ISSN 1087-1845
O'Hanlon, Karen and Margison, Geoffrey P. and Hatch, Amy and Fitzpatrick, David A. and Owens, Rebecca A. and Doyle, Sean and Jones, Gary W. (2012) Molecular characterization of an adaptive response to alkylating agents in the opportunistic pathogen Aspergillus fumigatus. Nucleic Acids Research, 40 (16). pp. 7806-7820. ISSN 0305-1048
Gallagher, Lorna and Owens, Rebecca A. and Dolan, Stephen K. and O'Keefe, Grainne and Schrettl, Markus and Kavanagh, Kevin and Jones, Gary W. and Doyle, Sean (2012) The Aspergillus fumigatus Protein GliK Protects against Oxidative Stress and Is Essential for Gliotoxin Biosynthesis. Eukaryotic Cell, 11 (10). pp. 1226-1238. ISSN 1535-9778
Fitzpatrick, David A. and O'Brien, Jennifer and Moran, Ciara and Hasin, Naushaba and Kenny, Elaine and Cormican, Paul and Gates, Amy and Morris, Derek W. and Jones, Gary W. (2011) Assessment of Inactivating Stop Codon Mutations in Forty Saccharomyces cerevisiae Strains: Implications for [PSI+] Prion-Mediated Phenotypes. PLoS ONE, 6 (12). e28684. ISSN 1932-6203
Medina, Edgar M. and Jones, Gary W. and Fitzpatrick, David A. (2011) Reconstructing the Fungal Tree of Life Using Phylogenomics and a Preliminary Investigation of the Distribution of Yeast Prion-Like Proteins in the Fungal Kingdom. Journal of Molecular Evolution, 73 (3-4). pp. 116-133. ISSN 0022-2844
Schrettl, Markus and Carberry, Stephen and Kavanagh, Kevin and Haas, Hubertus and Jones, Gary W. and O'Brien, Jennifer and Nolan, Aine and Stephens, John C. and Fenelon, Orla and Doyle, Sean (2010) Self-Protection against Gliotoxin—A Component of the Gliotoxin Biosynthetic Cluster, GliT, Completely Protects Aspergillus fumigatus Against Exogenous Gliotoxin. PLOS Pathogens, 6 (6). ISSN 1553-7366
Jones, Gary W. and Tuite, M.F. (2005) Chaperoning prions: the cellular machinery for propagating an infectious protein? BioEssays, 27. pp. 823-832.
