Jameson, Gráinne, Harmon, Cathal, Santiago, Rhyla Mae, Houlihan, Diarmaid D., Gallagher, Tom K., Lynch, Lydia, Robinson, Mark W. and O’Farrelly, Cliona (2022) Human Hepatic CD56bright NK Cells Display a Tissue-Resident Transcriptional Profile and Enhanced Ability to Kill Allogenic CD8+ T Cells. Frontiers in Immunology, 13. pp. 1-14. ISSN 1664-3224
Dyck, Lydia, Prendeville, Hannah, Raverdeau, Mathilde, Wilk, Mieszko M., Loftus, Roisin M., Douglas, Aaron, McCormack, Janet, Moran, Bruce, Wilkinson, Michael, Mills, Evanna L., Doughty, Michael, Fabre, Aurelie, Heneghan, Helen, LeRoux, Carel, Hogan, Andrew E., Chouchani, Edward T., O’Shea, Donal, Brennan, Donal and Lynch, Lydia (2022) Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function. Journal of Experimental Medicine, 219 (3). ISSN 0022-1007
O'Brien, Aisling, Loftus, Roisin M., Pisarska, Marta M., Tobin, Laura M., Bergin, Ronan, Wood, Nicole A.W., Foley, Cathriona, Mat, Arimin, Tinley, Frances C., Bannan, Ciaran, Sommerville, Gary, Veerapen, Natacha, Besra, Gurdyal S., Sinclair, Linda V., Moynagh, Paul N., Lynch, Lydia, Finlay, David K., O'Shea, Donal and Hogan, Andrew E. (2019) Obesity Reduces mTORC1 Activity in Mucosal-Associated Invariant T Cells, Driving Defective Metabolic and Functional Responses. Journal of Immunology, 202. pp. 3404-3411. ISSN 0022-1767
Harmon, Cathal, Robinson, Mark W., Hand, Fiona, Almuaili, Dalal, Mentor, Keno, Houlihan, Diarmaid D., Hoti, Emir, Lynch, Lydia, Geoghegan, Justin and O'Farrelly, Cliona (2018) Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of LiverResident NK Cells in Colorectal Liver Metastasis. Cancer Immunology Research, 7 (2). p. 2018. ISSN 2326-6066
Michelet, Xavier, Dyck, Lydia, Hogan, Andrew E., Loftus, Roisin, Duquette, Danielle, Wei, Kevin, Beyaz, Semir, Tavakkoli, Ali, Foley, Cathriona, Donnelly, Raymond, O'Farrelly, Cliona, Raverdeau, Mathilde, Veron, Ashley, Pettee, William, O'Shea, Donal, Nikolajczyk, Barbara S, Mills, Kingston H.G., Brenner, Michael B., Finlay, David and Lynch, Lydia (2018) Metabolic reprogramming of natural killer cells in obesity limits antitumor responses. Nature Immunology, 19. pp. 1330-1340. ISSN 1529-2908
Boulenouar, Selma, Michelet, Xavier, Duquette, Danielle, Alvarez, Daniel, Hogan, Andrew E., Dold, Christina, O’Connor, Donal, Stutte, Suzanne, Tavakkoli, Ali, Winters, Desmond, Exley, Mark A., O'Shea, Donal, Brenner, Michael B., von Andrian, Ulrich and Lynch, Lydia (2017) Adipose Type One Innate Lymphoid Cells Regulate Macrophage Homeostasis through Targeted Cytotoxicity. Immunity, 46 (2). pp. 273-286. ISSN 1097-4180
Lynch, Lydia, Hogan, Andrew E., Duquette, Danielle, O'Shea, Donal and Brenner, Michael B. (2016) iNKT Cells Induce FGF21 for Thermogenesis and Are Required for Maximal Weight Loss in GLP1 Therapy. Cell Metabolism, 24. pp. 510-519. ISSN 1550-4131
Carolan, Eirin, Tobin, Laura M., Mangan, Bozgana A., Corrigan, Michelle, Gaoatswe, Gadintshware, Byrne, Greg, Geoghegan, Justin, Cody, Declan, O'Connell, Jean, Winter, Desmond C, Doherty, Derek G., Lynch, Lydia, O'Shea, Donal and Hogan, Andrew E. (2015) Altered Distribution and Increased IL-17 Production by Mucosal-Associated Invariant T Cells in Adult and Childhood Obesity. Journal of Immunology, 194 (12). pp. 5775-5780. ISSN 0022-1767
Hogan, Andrew E., Gaoatswe, Gadintshware, Lynch, Lydia, Corrigan, Michelle, Woods, Conor, O'Connell, Jean and O'Shea, Donal (2014) Glucagon-like peptide 1 analogue therapy directly modulates innate immune-mediated inflammation in individuals with type 2 diabetes mellitus. Diabetologia, 57. pp. 781-784. ISSN 0012-186X
Lynch, Lydia, Nowak, Michael, Varghese, Bindu, Clark, Justice, Hogan, Andrew E., Toxavidis, Vasillis, Balk, Steven P., O'Shea, Donal, O'Farrelly, Cliona and Exley, Mark A. (2012) Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production. Immunity, 37 (3). pp. 574-587. ISSN 1097-4180
Hogan, Andrew E., Corrigan, Michelle, O'Reilly, Vincent P., Gaoatswe, G., O'Connell, Jean, Doherty, Derek G., Lynch, Lydia and O'Shea, Donal (2011) Cigarette smoke alters the invariant natural killer T cell function and may inhibit anti-tumor responses. Clinical Immunology, 140. pp. 229-235. ISSN 1521-6616
Hogan, Andrew E., Tobin, A.M., Ahern, T., Corrigan, Michelle, Gaoatswe, Gadintshware, Jackson, Ruaidhri, O’Reilly, Vincent P., Lynch, Lydia, Doherty, D.G., Moynagh, Paul N., Kirby, B., O’Connell, Jean and O'Shea, Donal (2011) Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer Tcells: lessons from obesity, diabetes and psoriasis. Diabetologia, 54 (11). pp. 2745-2754. ISSN 0012-186X