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    Chaperoning prions: the story unfolds

    O'Connor, David and Jones, Gary (2006) Chaperoning prions: the story unfolds. Biotech International (18). pp. 6-10.

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    Prions are infectious proteins that are responsible for a number of mammalian degenerative diseases. The discovery of prions in yeast has allowed detailed genetic analysis to be carried out to identify cellular factors involved in prion propagation. It is now clear that a complex relationship exists between molecular chaperones and prion propagation. Prions may actually have evolved to exploit the cell's chaperone machinery to ensure their own propagation.

    Item Type: Article
    Keywords: prions; prion propagation; chaperones; yeast;
    Academic Unit: Faculty of Science and Engineering > Research Institutes > Hamilton Institute
    Item ID: 6020
    Identification Number:
    Depositing User: Dr. Gary Jones
    Date Deposited: 10 Apr 2015 16:12
    Journal or Publication Title: Biotech International
    Publisher: PanGlobal Media
    Refereed: No
      Use Licence: This item is available under a Creative Commons Attribution Non Commercial Share Alike Licence (CC BY-NC-SA). Details of this licence are available here

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