Article

Ting, Kay Reen, Henry, Michael, Meiller, Justine, Larkin, Annemarie, Clynes, Martin, Meleady, Paula, Bazou, Despina, Dowling, Paul and O'Gorman, Peter (2017) Novel panel of protein biomarkers to predict response to bortezomib-containing induction regimens in multiple myeloma patients. BBA Clinical, 8. pp. 28-34. ISSN 2214-6474

Hmmier, Abduladim, O'Brien, Michael Emmet, Lynch, Vincent, Clynes, Martin, Morgan, Ross and Dowling, Paul (2017) Proteomic analysis of bronchoalveolar lavage fluid (BALF) from lung cancer patients using label-free mass spectrometry. BBA Clinical, 7. pp. 97-104. ISSN 2214-6474

O'Sullivan, Dermot, Dowling, Paul, Joyce, Helena, McAuley, Edel, McCann, Andrew, Henry, Michael, McGovern, Brianan, Barham, Paul, Kelleher, Fergal C., Murphy, Jean, Kennedy, Susan, Swan, Niall, Moriarty, Michael, Clynes, Martin and Larkin, Annemarie (2017) A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer. British Journal of Cancer, 117 (9). pp. 1326-1335. ISSN 1532-1827

Moloney, Nicola M., Owens, Rebecca A., Meleady, Paula, Henry, Michael, Dolan, Stephen K., Mulvihill, Eoin, Clynes, Martin and Doyle, Sean (2016) The iron-responsive microsomal proteome of Aspergillus fumigatus. Journal of Proteomics, 136. pp. 99-111. ISSN 1874-3919

Browne, Niall, Surlis, Carla, Maher, Amie, Gallagher, Clair, Carolan, James C., Clynes, Martin and Kavanagh, Kevin (2015) Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection. Virulence, 6 (5). pp. 458-465. ISSN 2150-5594

O'Sullivan, Dermot, Henry, Michael, Joyce, Helena, Walsh, Naomi, Mc Auley, Edel, Dowling, Paul, Swan, Niall, Moriarty, Michael, Barnham, Paul, Clynes, Martin and Larkin, Annemarie (2014) 7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells. Tumor Biology, 35 (7). pp. 6983-6997. ISSN 1010-4283

McMahon, Frederick W., Gallagher, Clair, O'Reilly, Niamh, Clynes, Martin, O'Sullivan, Finbarr and Kavanagh, Kevin (2014) Exposure of a Corneal Epithelial Cell Line (hTCEpi) to Demodex-Associated Bacillus Proteins Results in an Inflammatory Response. Investigative Ophthalmology & Visual Science, 55 (10). pp. 7019-7028. ISSN 0146-0404

Holland, Ashling, Schmitt-John, Thomas, Dowling, Paul, Meleady, Paula, Henry, Michael, Clynes, Martin and Ohlendieck, Kay (2014) Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry. Bioscience Reports, 34 (4). pp. 331-343. ISSN 1573-4935

McDermott, Martina S.J., Browne, Brigid C., Conlon, Neil T., O'Brien, Neil A., Slamon, Dennis J., Henry, Michael, Meleady, Paula, Clynes, Martin, Dowling, Paul, Crown, John and O'Donovan, Norma (2014) PP2A inhibition overcomes acquired resistance to HER2 targeted therapy. Molecular Cancer, 13 (157). pp. 1-12. ISSN 1476-4598

Holland, Ashling, Dowling, Paul, Zweyer, Margit, Swandulla, Dieter, Henry, Michael, Clynes, Martin and Ohlendieck, Kay (2013) Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin. Proteomics, 13 (15). pp. 2312-2323. ISSN 1615-9853

Dowling, Paul, Clarke, Colin, Hennessy, Kim, Torralbo-Lopez, Beatriz, Ballot, Jo, Crown, John, Kiernan, Ingrid, O'Byrne, Kenneth J., Kennedy, M. John, Lynch, Vincent and Clynes, Martin (2012) Analysis of acute-phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer. International Journal of Cancer, 131 (4). pp. 911-923. ISSN 0020-7136

O'Reilly, Niamh, Gallagher, Clair, Reddy Katikireddy, Kishore, Clynes, Martin, O'Sullivan, Finbarr and Kavanagh, Kevin (2012) Demodex-Associated Bacillus Proteins Induce an Aberrant Wound Healing Response in a Corneal Epithelial Cell Line: Possible Implications for Corneal Ulcer Formation in Ocular Rosacea. Investigative Ophthalmology & Visual Science, 53. pp. 3250-3259. ISSN 0146-0404

Keenan, Joanne, Joyce, Helena, Aherne, Sinead, O'Dea, Shirley, Doolan, Padraig, Lynch, Vincent and Clynes, Martin (2012) Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line. Experimental Cell Research, 318 (5). pp. 593-602. ISSN 0014-4827

Eustace, Alex J., Dowling, Paul, Henry, Michael, Doolan, Padraig, Meleady, Paula, Clynes, Martin, Crown, John and O'Donovan, Norma (2011) 2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines. Journal of Proteomics, 74 (4). pp. 490-501. ISSN 1874-3919

Dowling, Paul and Clynes, Martin (2011) Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of diseasespecific biomarkers. Proteomics, 11 (4). pp. 794-804. ISSN 1615-9853

Walsh, Naomi, Larkin, Annemarie, Swan, Niall, Conlon, Kevin, Dowling, Paul, McDermott, Ray and Clynes, Martin (2011) RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation. Cancer Letters, 306 (2). pp. 180-189. ISSN 0304-3835

Rajpal, Rajesh, Dowling, Paul, Meiller, Justine, Clarke, Colin, Murphy, William G., O'Connor, Robert, Kell, Malcolm, Mitsiades, Constantine, Richardson, Paul, Anderson, Kenneth C., Clynes, Martin and O'Gorman, Peter (2011) A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients. Proteomics, 11 (8). pp. 1391-1402. ISSN 1615-9853

Walsh, Naomi, O'Donovan, Norma, Kennedy, Susan, Henry, Michael, Meleady, Paula, Clynes, Martin and Dowling, Paul (2009) Identification of pancreatic cancer invasion-related proteins by proteomic analysis. Proteome Science, 7 (3). ISSN 1477-5956

Muniyappa, M.K., Dowling, Paul, Henry, M., Meleady, Paula, Doolan, P., Gammell, P., Clynes, Martin and Barron, N. (2009) MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. European Journal of Cancer, 45 (17). pp. 3104-3118. ISSN 0959-8049

Walsh, Naomi, Dowling, Paul, O'Donovan, Norma, Henry, Michael, Meleady, Paula and Clynes, Martin (2008) Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells. Journal of Proteomics, 71 (5). pp. 561-571. ISSN 1874-3919

Dowling, Paul, Wormald, Robert, Meleady, Paula, Henry, Michael, Curran, Aongus and Clynes, Martin (2008) Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis. Journal of Proteomics, 71 (2). pp. 168-175. ISSN 1874-3919

Dowling, Paul, Walsh, Naomi and Clynes, Martin (2008) Membrane and membrane-associated proteins involved in the aggressive phenotype displayed by highly invasive cancer cells. Proteomics, 8 (19). pp. 4054-4065. ISSN 1615-9853

Kumar, Niraj, Maurya, Priyanka, Gammell, Patrick, Dowling, Paul, Clynes, Martin and Meleady, Paula (2008) Proteomic Profiling of Secreted Proteins from CHO Cells Using Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry. Biotechnology Progress, 24 (1). pp. 273-278. ISSN 8756-7938

Dowling, Paul, Shields, William, Rani, Sweta, Meleady, Paula, Henry, Michael, Jeppesen, Per Bendix, O'Driscoll, Lorraine and Clynes, Martin (2008) Proteomic analysis of conditioned media from glucose responsive and glucose nonresponsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction. Electrophoresis, 29 (20). pp. 4141-4149. ISSN 0173-0835

Dowling, Paul, O'Driscoll, Lorraine, Meleady, Paula, Henry, Michael, Roy, Shunil, Ballot, Jo, Moriarty, Michael, Crown, John and Clynes, Martin (2007) 2-D difference gel electrophoresis of the lung squamous cell carcinoma versus normal sera demonstrates consistent alterations in the levels of ten specific proteins. Electrophoresis, 28 (23). pp. 4302-4310. ISSN 0173-0835

Dowling, Paul, Meleady, Paula, Dowd, Andrew, Henry, Michael, Glynn, Sharon and Clynes, Martin (2007) Proteomic analysis of isolated membrane fractions from superinvasive cancer cells. Biochimica et Biophysica Acta - Proteins and Proteomics, 1774 (1). pp. 93-101. ISSN 1570-9639

Dowling, Paul, Maurya, Priyanka, Meleady, Paula, Glynn, Sharon, Dowd, Andrew, Henry, Michael and Clynes, Martin (2007) Purification and Identification of a 7.6-kDa Protein in Media Conditioned by Superinvasive Cancer Cells. Anticancer Research, 27 (3A). pp. 1309-1317. ISSN 0250-7005

Bergin, David, Murphy, Lisa, Keenan, Joanne, Clynes, Martin and Kavanagh, Kevin (2006) Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides. Microbes and Infection, 8 (8). pp. 2105-2112. ISSN 1769-714X

Dowling, Paul, O'Driscoll, Lorraine, O'Sullivan, Finbarr, Dowd, Andrew, Henry, Michael, Jeppesen, Per Bendix, Meleady, Paula and Clynes, Martin (2006) Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress. Proteomics, 6 (24). pp. 6578-6587. ISSN 1615-9853

Coyle, Barry, Kinsella, Paula, McCann, Malachy, Devereux, Michael, O'Connor, Robert, Clynes, Martin and Kavanagh, Kevin (2004) Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes. Toxicology in Vitro, 18 (1). pp. 63-70.

McCann, Malachy, Coyle, Barry, McKay, Sinead, McCormack, Paul, Kavanagh, Kevin, Devereux, Michael, McKee, Vickie, Kinsella, Paula, O'Connor, Robert and Clynes, Martin (2004) Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells. Biometals, 17 (6). pp. 635-645. ISSN 0966-0844

McBride, Shirley, Walsh, Derek, Meleady, Paula, Daly, Noel and Clynes, Martin (1999) Bromodeoxyuridine induces keratin protein synthesis at a posttranscriptional level in human lung tumour cell lines. Differentiation, 64. pp. 184-193. ISSN 0301-4681

Daly, Paul, Verhaegen, Steven, Clynes, Martin and Kavanagh, Kevin (1999) Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines. Mycopathologia, 146 (2). pp. 67-74. ISSN 0301-486X

Duffy, C.P., Elliott, C.J., O'Connor, R.A., Heenan, M.M., Coyle, S., Cleary, I.M., Kavanagh, Kevin, Verhaegen, Steven, O'Loughlin, C.M., NicAmhlaoibh, R. and Clynes, Martin (1998) Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs). European Journal of Cancer, 34 (8). pp. 1250-1259. ISSN 0959-8049

McBride, Shirley, Meleady, Paula, Baird, Alan, Dinsdale, David and Clynes, Martin (1998) Human Lung Carcinoma Cell Line DLKP Contains 3 Distinct Subpopulations with Different Growth and Attachment Properties. Tumor Biology, 19. pp. 88-103. ISSN 1010-4283

Daly, Carmel, Coyle, Seamus, O'Dea, Shirley, O'Driscoll, Lorraine, Daly, Noel, Scanlon, Kevin and Clynes, Martin (1996) mdrl Ribozyme mediated reversal of the multi-drug resistant phenotype in human lung cell lines. Cytotechnology, 19. pp. 199-205. ISSN 0920-9069