Article

Ting, Kay Reen and Henry, Michael and Meiller, Justine and Larkin, Annemarie and Clynes, Martin and Meleady, Paula and Bazou, Despina and Dowling, Paul and O'Gorman, Peter (2017) Novel panel of protein biomarkers to predict response to bortezomib-containing induction regimens in multiple myeloma patients. BBA Clinical, 8. pp. 28-34. ISSN 2214-6474

Hmmier, Abduladim and O'Brien, Michael Emmet and Lynch, Vincent and Clynes, Martin and Morgan, Ross and Dowling, Paul (2017) Proteomic analysis of bronchoalveolar lavage fluid (BALF) from lung cancer patients using label-free mass spectrometry. BBA Clinical, 7. pp. 97-104. ISSN 2214-6474

O'Sullivan, Dermot and Dowling, Paul and Joyce, Helena and McAuley, Edel and McCann, Andrew and Henry, Michael and McGovern, Brianan and Barham, Paul and Kelleher, Fergal C. and Murphy, Jean and Kennedy, Susan and Swan, Niall and Moriarty, Michael and Clynes, Martin and Larkin, Annemarie (2017) A novel inhibitory anti-invasive MAb isolated using phenotypic screening highlights AnxA6 as a functionally relevant target protein in pancreatic cancer. British Journal of Cancer, 117 (9). pp. 1326-1335. ISSN 1532-1827

Moloney, Nicola M. and Owens, Rebecca A. and Meleady, Paula and Henry, Michael and Dolan, Stephen K. and Mulvihill, Eoin and Clynes, Martin and Doyle, Sean (2016) The iron-responsive microsomal proteome of Aspergillus fumigatus. Journal of Proteomics, 136. pp. 99-111. ISSN 1874-3919

Browne, Niall and Surlis, Carla and Maher, Amie and Gallagher, Clair and Carolan, James C. and Clynes, Martin and Kavanagh, Kevin (2015) Prolonged pre-incubation increases the susceptibility of Galleria mellonella larvae to bacterial and fungal infection. Virulence, 6 (5). pp. 458-465. ISSN 2150-5594

O'Sullivan, Dermot and Henry, Michael and Joyce, Helena and Walsh, Naomi and Mc Auley, Edel and Dowling, Paul and Swan, Niall and Moriarty, Michael and Barnham, Paul and Clynes, Martin and Larkin, Annemarie (2014) 7B7: a novel antibody directed against the Ku70/Ku80 heterodimer blocks invasion in pancreatic and lung cancer cells. Tumor Biology, 35 (7). pp. 6983-6997. ISSN 1010-4283

McMahon, Frederick W. and Gallagher, Clair and O'Reilly, Niamh and Clynes, Martin and O'Sullivan, Finbarr and Kavanagh, Kevin (2014) Exposure of a Corneal Epithelial Cell Line (hTCEpi) to Demodex-Associated Bacillus Proteins Results in an Inflammatory Response. Investigative Ophthalmology & Visual Science, 55 (10). pp. 7019-7028. ISSN 0146-0404

Holland, Ashling and Schmitt-John, Thomas and Dowling, Paul and Meleady, Paula and Henry, Michael and Clynes, Martin and Ohlendieck, Kay (2014) Intricate effects of primary motor neuronopathy on contractile proteins and metabolic muscle enzymes as revealed by label-free mass spectrometry. Bioscience Reports, 34 (4). pp. 331-343. ISSN 1573-4935

McDermott, Martina S.J. and Browne, Brigid C. and Conlon, Neil T. and O'Brien, Neil A. and Slamon, Dennis J. and Henry, Michael and Meleady, Paula and Clynes, Martin and Dowling, Paul and Crown, John and O'Donovan, Norma (2014) PP2A inhibition overcomes acquired resistance to HER2 targeted therapy. Molecular Cancer, 13 (157). pp. 1-12. ISSN 1476-4598

Holland, Ashling and Dowling, Paul and Zweyer, Margit and Swandulla, Dieter and Henry, Michael and Clynes, Martin and Ohlendieck, Kay (2013) Proteomic profiling of cardiomyopathic tissue from the aged mdx model of Duchenne muscular dystrophy reveals a drastic decrease in laminin, nidogen and annexin. Proteomics, 13 (15). pp. 2312-2323. ISSN 1615-9853

Dowling, Paul and Clarke, Colin and Hennessy, Kim and Torralbo-Lopez, Beatriz and Ballot, Jo and Crown, John and Kiernan, Ingrid and O'Byrne, Kenneth J. and Kennedy, M. John and Lynch, Vincent and Clynes, Martin (2012) Analysis of acute-phase proteins, AHSG, C3, CLI, HP and SAA, reveals distinctive expression patterns associated with breast, colorectal and lung cancer. International Journal of Cancer, 131 (4). pp. 911-923. ISSN 0020-7136

O'Reilly, Niamh and Gallagher, Clair and Reddy Katikireddy, Kishore and Clynes, Martin and O'Sullivan, Finbarr and Kavanagh, Kevin (2012) Demodex-Associated Bacillus Proteins Induce an Aberrant Wound Healing Response in a Corneal Epithelial Cell Line: Possible Implications for Corneal Ulcer Formation in Ocular Rosacea. Investigative Ophthalmology & Visual Science, 53. pp. 3250-3259. ISSN 0146-0404

Keenan, Joanne and Joyce, Helena and Aherne, Sinead and O'Dea, Shirley and Doolan, Padraig and Lynch, Vincent and Clynes, Martin (2012) Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line. Experimental Cell Research, 318 (5). pp. 593-602. ISSN 0014-4827

Eustace, Alex J. and Dowling, Paul and Henry, Michael and Doolan, Padraig and Meleady, Paula and Clynes, Martin and Crown, John and O'Donovan, Norma (2011) 2D-DIGE analysis of phospho-enriched fractions from dasatinib-treated melanoma cell lines. Journal of Proteomics, 74 (4). pp. 490-501. ISSN 1874-3919

Dowling, Paul and Clynes, Martin (2011) Conditioned media from cell lines: A complementary model to clinical specimens for the discovery of diseasespecific biomarkers. Proteomics, 11 (4). pp. 794-804. ISSN 1615-9853

Walsh, Naomi and Larkin, Annemarie and Swan, Niall and Conlon, Kevin and Dowling, Paul and McDermott, Ray and Clynes, Martin (2011) RNAi knockdown of Hop (Hsp70/Hsp90 organising protein) decreases invasion via MMP-2 down regulation. Cancer Letters, 306 (2). pp. 180-189. ISSN 0304-3835

Rajpal, Rajesh and Dowling, Paul and Meiller, Justine and Clarke, Colin and Murphy, William G. and O'Connor, Robert and Kell, Malcolm and Mitsiades, Constantine and Richardson, Paul and Anderson, Kenneth C. and Clynes, Martin and O'Gorman, Peter (2011) A novel panel of protein biomarkers for predicting response to thalidomide-based therapy in newly diagnosed multiple myeloma patients. Proteomics, 11 (8). pp. 1391-1402. ISSN 1615-9853

Walsh, Naomi and O'Donovan, Norma and Kennedy, Susan and Henry, Michael and Meleady, Paula and Clynes, Martin and Dowling, Paul (2009) Identification of pancreatic cancer invasion-related proteins by proteomic analysis. Proteome Science, 7 (3). ISSN 1477-5956

Muniyappa, M.K. and Dowling, Paul and Henry, M. and Meleady, Paula and Doolan, P. and Gammell, P. and Clynes, Martin and Barron, N. (2009) MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. European Journal of Cancer, 45 (17). pp. 3104-3118. ISSN 0959-8049

Walsh, Naomi and Dowling, Paul and O'Donovan, Norma and Henry, Michael and Meleady, Paula and Clynes, Martin (2008) Aldehyde dehydrogenase 1A1 and gelsolin identified as novel invasion-modulating factors in conditioned medium of pancreatic cancer cells. Journal of Proteomics, 71 (5). pp. 561-571. ISSN 1874-3919

Dowling, Paul and Wormald, Robert and Meleady, Paula and Henry, Michael and Curran, Aongus and Clynes, Martin (2008) Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis. Journal of Proteomics, 71 (2). pp. 168-175. ISSN 1874-3919

Dowling, Paul and Walsh, Naomi and Clynes, Martin (2008) Membrane and membrane-associated proteins involved in the aggressive phenotype displayed by highly invasive cancer cells. Proteomics, 8 (19). pp. 4054-4065. ISSN 1615-9853

Kumar, Niraj and Maurya, Priyanka and Gammell, Patrick and Dowling, Paul and Clynes, Martin and Meleady, Paula (2008) Proteomic Profiling of Secreted Proteins from CHO Cells Using Surface-Enhanced Laser Desorption Ionization Time-of-Flight Mass Spectrometry. Biotechnology Progress, 24 (1). pp. 273-278. ISSN 8756-7938

Dowling, Paul and Shields, William and Rani, Sweta and Meleady, Paula and Henry, Michael and Jeppesen, Per Bendix and O'Driscoll, Lorraine and Clynes, Martin (2008) Proteomic analysis of conditioned media from glucose responsive and glucose nonresponsive phenotypes reveals a panel of secreted proteins associated with beta cell dysfunction. Electrophoresis, 29 (20). pp. 4141-4149. ISSN 0173-0835

Dowling, Paul and O'Driscoll, Lorraine and Meleady, Paula and Henry, Michael and Roy, Shunil and Ballot, Jo and Moriarty, Michael and Crown, John and Clynes, Martin (2007) 2-D difference gel electrophoresis of the lung squamous cell carcinoma versus normal sera demonstrates consistent alterations in the levels of ten specific proteins. Electrophoresis, 28 (23). pp. 4302-4310. ISSN 0173-0835

Dowling, Paul and Meleady, Paula and Dowd, Andrew and Henry, Michael and Glynn, Sharon and Clynes, Martin (2007) Proteomic analysis of isolated membrane fractions from superinvasive cancer cells. Biochimica et Biophysica Acta - Proteins and Proteomics, 1774 (1). pp. 93-101. ISSN 1570-9639

Dowling, Paul and Maurya, Priyanka and Meleady, Paula and Glynn, Sharon and Dowd, Andrew and Henry, Michael and Clynes, Martin (2007) Purification and Identification of a 7.6-kDa Protein in Media Conditioned by Superinvasive Cancer Cells. Anticancer Research, 27 (3A). pp. 1309-1317. ISSN 0250-7005

Bergin, David and Murphy, Lisa and Keenan, Joanne and Clynes, Martin and Kavanagh, Kevin (2006) Pre-exposure to yeast protects larvae of Galleria mellonella from a subsequent lethal infection by Candida albicans and is mediated by the increased expression of antimicrobial peptides. Microbes and Infection, 8 (8). pp. 2105-2112. ISSN 1769-714X

Dowling, Paul and O'Driscoll, Lorraine and O'Sullivan, Finbarr and Dowd, Andrew and Henry, Michael and Jeppesen, Per Bendix and Meleady, Paula and Clynes, Martin (2006) Proteomic screening of glucose-responsive and glucose non-responsive MIN-6 beta cells reveals differential expression of proteins involved in protein folding, secretion and oxidative stress. Proteomics, 6 (24). pp. 6578-6587. ISSN 1615-9853

Coyle, Barry and Kinsella, Paula and McCann, Malachy and Devereux, Michael and O'Connor, Robert and Clynes, Martin and Kavanagh, Kevin (2004) Induction of apoptosis in yeast and mammalian cells by exposure to 1,10-phenanthroline metal complexes. Toxicology in Vitro, 18 (1). pp. 63-70.

McCann, Malachy and Coyle, Barry and McKay, Sinead and McCormack, Paul and Kavanagh, Kevin and Devereux, Michael and McKee, Vickie and Kinsella, Paula and O'Connor, Robert and Clynes, Martin (2004) Synthesis and X-ray crystal structure of [Ag(phendio)2]ClO4 (phendio = 1,10-phenanthroline-5,6-dione) and its effects on fungal and mammalian cells. Biometals, 17 (6). pp. 635-645. ISSN 0966-0844

McBride, Shirley and Walsh, Derek and Meleady, Paula and Daly, Noel and Clynes, Martin (1999) Bromodeoxyuridine induces keratin protein synthesis at a posttranscriptional level in human lung tumour cell lines. Differentiation, 64. pp. 184-193. ISSN 0301-4681

Daly, Paul and Verhaegen, Steven and Clynes, Martin and Kavanagh, Kevin (1999) Culture filtrates of Aspergillus fumigatus induce different modes of cell death in human cancer cell lines. Mycopathologia, 146 (2). pp. 67-74. ISSN 0301-486X

Duffy, C.P. and Elliott, C.J. and O'Connor, R.A. and Heenan, M.M. and Coyle, S. and Cleary, I.M. and Kavanagh, Kevin and Verhaegen, Steven and O'Loughlin, C.M. and NicAmhlaoibh, R. and Clynes, Martin (1998) Enhancement of chemotherapeutic drug toxicity to human tumour cells in vitro by a subset of non-steroidal anti-inflammatory drugs (NSAIDs). European Journal of Cancer, 34 (8). pp. 1250-1259. ISSN 0959-8049

McBride, Shirley and Meleady, Paula and Baird, Alan and Dinsdale, David and Clynes, Martin (1998) Human Lung Carcinoma Cell Line DLKP Contains 3 Distinct Subpopulations with Different Growth and Attachment Properties. Tumor Biology, 19. pp. 88-103. ISSN 1010-4283

Daly, Carmel and Coyle, Seamus and O'Dea, Shirley and O'Driscoll, Lorraine and Daly, Noel and Scanlon, Kevin and Clynes, Martin (1996) mdrl Ribozyme mediated reversal of the multi-drug resistant phenotype in human lung cell lines. Cytotechnology, 19. pp. 199-205. ISSN 0920-9069